The possibility is shown to use optical methods of measurement of suspension transparency and holographic techniques of diagnostics of spatial particles ensembles simultaneously for nondestructive testing of microstructure parameters of water suspensions in biology, medicine, and environmental control. On the basis of calculated and experimental results, characteristics of the above methods are analyzed in the paper. We propose an optical scheme allowed us to realize both base method of measurement of suspension transparency and holographic technique with image transfer. An estimations have showed possibility of measurement of attenuation from about 10 -5. An allowable size of holographing microparticles is no less than 2 micrometers in a volume of several cm 3 and more in dependence on the particle size and number density. These estimations demonstrate the possibility to use the above methods for investigation of natural media. We also propose in this paper some potential applications of these methods.