Development of a high-resolution apparatus to monitor physiological state of a person undergoing extreme conditions

The present research has shown that ECG recordings and parameters of the body functional state are crucial for all kinds of the astronaut pre-flight preparations (centrifuge, thermal chamber, pressure chamber, pressure chamber with special equipment). It is, therefore, important to develop methods and tools for early detection of the preclinical forms of the functional state disorders in patients undergoing high-intensity loads of mixed character. The method based on the hardware-software comple? (HSC) with nanosensors of high resolution has been proposed to measure the electrophysiological characteristics and bioelectrical impedance of the body tissues directly exposed to loading. The hardware-software comple? is subjected to clinical trials in Tomsk Research Institute for Cardiology. The obtained results show that the use of nanosensors of high resolution in the HSC without standard filters allows elimination of the power-line interference in ECG recordings. Monitoring of the tissue bioimpedance parameters under test loads enables the detection of preclinical (latent) forms of various diseases. After clinical trials in Tomsk Institute for Cardiology the developed apparatus will be proposed for in-depth study of the cardiovascular system and the functional state of the body of astronauts and other persons exposed to extreme loads.