Determination of Sulfamethizole Using Voltammetry and Amperometry on Carbon Paste Electrode

Hana Dejmkova, Miroslav Mikes, Jiri Barek, Jiri Zima

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


Two methods for the determination of sulfamethizole on a carbon paste electrode (CPE) in pharmaceutical and urine samples were developed, using differential pulse voltammetry (DPV) and HPLC with amperometric detection. The voltammetric method is advantageous because of the undemanding sample treatment and quick, inexpensive and reliable determination and it is applicable for the sulfamethizole determination in pharmaceutical formulations. The chromatographic method was combined with SPE extraction. It provides higher selectivity and sensitivity while keeping the simple and inexpensive arrangement and allows the determination of sulfamethizole in a biological matrix.

Original languageEnglish
Pages (from-to)189-194
Number of pages6
Issue number1
Publication statusPublished - 1 Jan 2013
Externally publishedYes


  • Carbon paste electrode
  • Differential pulse voltammetry
  • HPLC
  • Pharmaceutical
  • Sulfonamide

ASJC Scopus subject areas

  • Analytical Chemistry
  • Electrochemistry

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