Abstract
Nine aromatic amines, i.e., benzidine; o-tolidine; o-dianisidine; 3,3’-dichlorobenzidine; 4-aminobiphenyl; 1- and 2-naphthylamine; 4,4’-methylene bis(2-chloroaniline) and m-toluenediamine were oxidized with potassium permanganate/sulfuric acid. Experimental conditions for complete degradation of these aromatic amines are described. The disappearance of the parent compound through oxidation was measured using HPLC coupled with UV spectrophotometry. The corresponding degradation products were found to be non-mutagenic to Salmonella typhimurium strains TA100, TA98 and TA97, both in the presence and absence of a rat liver S9 activation system. A collaborative study, involving 11 laboratories, has shown the applicability and the reproducibility of this degradation method.
| Original language | English |
|---|---|
| Pages (from-to) | 187-191 |
| Number of pages | 5 |
| Journal | American Industrial Hygiene Association Journal |
| Volume | 46 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1 Apr 1985 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
Cite this
Destruction of Aromatic Amines in Laboratory Wastes Through Oxidation with Potassium Permanganate/Sulfuric Acid into Non-mutagenic Derivatives. / Castegnaro, Marcel; Malaveilli, Christian; Broue, Isabelle; Michelon, Jocelyne; Barek, Jiri.
In: American Industrial Hygiene Association Journal, Vol. 46, No. 4, 01.04.1985, p. 187-191.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Destruction of Aromatic Amines in Laboratory Wastes Through Oxidation with Potassium Permanganate/Sulfuric Acid into Non-mutagenic Derivatives
AU - Castegnaro, Marcel
AU - Malaveilli, Christian
AU - Broue, Isabelle
AU - Michelon, Jocelyne
AU - Barek, Jiri
PY - 1985/4/1
Y1 - 1985/4/1
N2 - Nine aromatic amines, i.e., benzidine; o-tolidine; o-dianisidine; 3,3’-dichlorobenzidine; 4-aminobiphenyl; 1- and 2-naphthylamine; 4,4’-methylene bis(2-chloroaniline) and m-toluenediamine were oxidized with potassium permanganate/sulfuric acid. Experimental conditions for complete degradation of these aromatic amines are described. The disappearance of the parent compound through oxidation was measured using HPLC coupled with UV spectrophotometry. The corresponding degradation products were found to be non-mutagenic to Salmonella typhimurium strains TA100, TA98 and TA97, both in the presence and absence of a rat liver S9 activation system. A collaborative study, involving 11 laboratories, has shown the applicability and the reproducibility of this degradation method.
AB - Nine aromatic amines, i.e., benzidine; o-tolidine; o-dianisidine; 3,3’-dichlorobenzidine; 4-aminobiphenyl; 1- and 2-naphthylamine; 4,4’-methylene bis(2-chloroaniline) and m-toluenediamine were oxidized with potassium permanganate/sulfuric acid. Experimental conditions for complete degradation of these aromatic amines are described. The disappearance of the parent compound through oxidation was measured using HPLC coupled with UV spectrophotometry. The corresponding degradation products were found to be non-mutagenic to Salmonella typhimurium strains TA100, TA98 and TA97, both in the presence and absence of a rat liver S9 activation system. A collaborative study, involving 11 laboratories, has shown the applicability and the reproducibility of this degradation method.
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UR - http://www.scopus.com/inward/citedby.url?scp=0021913792&partnerID=8YFLogxK
U2 - 10.1080/15298668591394635
DO - 10.1080/15298668591394635
M3 - Article
VL - 46
SP - 187
EP - 191
JO - Journal of Occupational and Environmental Hygiene
JF - Journal of Occupational and Environmental Hygiene
SN - 1545-9624
IS - 4
ER -