Abstract
Production of reactive oxygen species by neutrophils was analysed by a chemiluminometric method in the presence of luminol in ten healthy donors, eight patients with gastric cancer and ten patients with gastric precancer. The neutrophil chemiluminominescence response to recombinant tumour necrosis factor (rTNF) was almost five times lower in the gastric patients when compared with healthy donors and precancer patients. The chemiluminescence response to zymosan was decreased only in the gastric cancer patients with chemiluminescence index activation (CTNF)
| Original language | English |
|---|---|
| Pages (from-to) | 172-174 |
| Number of pages | 3 |
| Journal | Journal of Cancer Research and Clinical Oncology |
| Volume | 117 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Mar 1991 |
| Externally published | Yes |
Keywords
- Chemiluminescence
- Gastric cancer
- Neutrophil
- Tumour Necrosis Factor
- Zymosan
ASJC Scopus subject areas
- Oncology
- Cancer Research
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Cite this
Schepetkin, I. A., Cherdyntseva, N. V., Borunov, E. V., Skutina, I. L., & Naumov, S. A. (1991). Decreased luminol-dependent chemiluminescence response of neutrophils to recombinant human tumour necrosis factor in patients with gastric cancer. Journal of Cancer Research and Clinical Oncology, 117(2), 172-174. https://doi.org/10.1007/BF01613143