Decreased luminol-dependent chemiluminescence response of neutrophils to recombinant human tumour necrosis factor in patients with gastric cancer

Abstract

Production of reactive oxygen species by neutrophils was analysed by a chemiluminometric method in the presence of luminol in ten healthy donors, eight patients with gastric cancer and ten patients with gastric precancer. The neutrophil chemiluminominescence response to recombinant tumour necrosis factor (rTNF) was almost five times lower in the gastric patients when compared with healthy donors and precancer patients. The chemiluminescence response to zymosan was decreased only in the gastric cancer patients with chemiluminescence index activation (C_TNF)

Original language	English
Pages (from-to)	172-174
Number of pages	3
Journal	Journal of Cancer Research and Clinical Oncology
Volume	117
Issue number	2
DOIs	https://doi.org/10.1007/BF01613143
Publication status	Published - Mar 1991
Externally published	Yes

Keywords

Chemiluminescence
Gastric cancer
Neutrophil
Tumour Necrosis Factor
Zymosan

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1007/BF01613143

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Decreased luminol-dependent chemiluminescence response of neutrophils to recombinant human tumour necrosis factor in patients with gastric cancer. / Schepetkin, I. A.; Cherdyntseva, N. V.; Borunov, E. V.; Skutina, I. L.; Naumov, S. A.

In: Journal of Cancer Research and Clinical Oncology, Vol. 117, No. 2, 03.1991, p. 172-174.

Research output: Contribution to journal › Article › peer-review

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title = "Decreased luminol-dependent chemiluminescence response of neutrophils to recombinant human tumour necrosis factor in patients with gastric cancer",

abstract = "Production of reactive oxygen species by neutrophils was analysed by a chemiluminometric method in the presence of luminol in ten healthy donors, eight patients with gastric cancer and ten patients with gastric precancer. The neutrophil chemiluminominescence response to recombinant tumour necrosis factor (rTNF) was almost five times lower in the gastric patients when compared with healthy donors and precancer patients. The chemiluminescence response to zymosan was decreased only in the gastric cancer patients with chemiluminescence index activation (CTNF) ",

keywords = "Chemiluminescence, Gastric cancer, Neutrophil, Tumour Necrosis Factor, Zymosan",

author = "Schepetkin, {I. A.} and Cherdyntseva, {N. V.} and Borunov, {E. V.} and Skutina, {I. L.} and Naumov, {S. A.}",

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AU - Schepetkin, I. A.

AU - Cherdyntseva, N. V.

AU - Borunov, E. V.

AU - Skutina, I. L.

AU - Naumov, S. A.

PY - 1991/3

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KW - Chemiluminescence

KW - Gastric cancer

KW - Neutrophil

KW - Tumour Necrosis Factor

KW - Zymosan

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