Coulometric redox titrations of some biologically active thiols with iodine in methanol and bromine in acetic acid

Tibor J. Pastor, Jiří Barek

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The possibility of coulometric titrations of cysteine, 2-thio-uracil, 6-mercaptopurine, and 6-thioguanine with iodine and bromine in methanol and with bromine in acetic acid has been investigated. Conditions have been found for the direct titration of the test substances with iodine in methanol based on their 1-electron oxidation to the corresponding disulphides and for their direct and indirect determination with bromine in acetic acid based on their 6-electron oxidation to the corresponding sulphonic acids.

Original languageEnglish
Pages (from-to)407-413
Number of pages7
JournalMikrochimica Acta
Volume97
Issue number5-6
DOIs
Publication statusPublished - 1 Jan 1989
Externally publishedYes

Fingerprint

Bromine
Titration
Sulfhydryl Compounds
Acetic Acid
Iodine
Methanol
Thioguanine
6-Mercaptopurine
Oxidation
Sulfonic Acids
Uracil
Electrons
Disulfides
Cysteine
Oxidation-Reduction

Keywords

  • bromine
  • coulometry
  • iodine
  • thiols

ASJC Scopus subject areas

  • Analytical Chemistry

Cite this

Coulometric redox titrations of some biologically active thiols with iodine in methanol and bromine in acetic acid. / Pastor, Tibor J.; Barek, Jiří.

In: Mikrochimica Acta, Vol. 97, No. 5-6, 01.01.1989, p. 407-413.

Research output: Contribution to journalArticle

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