Coulometric redox titrations of some biologically active thiols with iodine in methanol and bromine in acetic acid

Tibor J. Pastor, Jiří Barek

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5 Citations (Scopus)


The possibility of coulometric titrations of cysteine, 2-thio-uracil, 6-mercaptopurine, and 6-thioguanine with iodine and bromine in methanol and with bromine in acetic acid has been investigated. Conditions have been found for the direct titration of the test substances with iodine in methanol based on their 1-electron oxidation to the corresponding disulphides and for their direct and indirect determination with bromine in acetic acid based on their 6-electron oxidation to the corresponding sulphonic acids.

Original languageEnglish
Pages (from-to)407-413
Number of pages7
JournalMikrochimica Acta
Issue number5-6
Publication statusPublished - 1 Jan 1989
Externally publishedYes



  • bromine
  • coulometry
  • iodine
  • thiols

ASJC Scopus subject areas

  • Analytical Chemistry

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