Correction of coronary failure by dihydropiridin antagonists of calcium in patients after coronary artery bypass surgery

A. T. Teplyakov, E. V. Rybalchenko, A. A. Garganeeva, V. I. Chernov

Research output: Contribution to journalArticlepeer-review

Abstract

Aim. To study antiischemic and antianginal efficiency of adalat and its prolonged form adalat SL, dihydropiridin antagonists of calcium, in patients 1-3 years after surgical correction of stenosing coronary atherosclerosis. Material and methods. The drugs were tried in 40 patients with angina of effort (functional class II-III) with a satisfactory inotropic-function of the left ventricle 1 to 3 years after coronary artery bypass surgery (CABS). Myocardial circulation was measured with one-photon emission computed tomography using 99m-Tc-MIBI (CT). Results. A 3-week therapy with adalat reduced the number of anginal attacks, nitroglycerin requirement, enhanced exercise tolerance. CT showed that myocardial blood flow significantly improved. Conclusion. Adalat proved to be effective in patients after CABS. Its prolonged form adalat SL is preferable.

Original languageEnglish
Pages (from-to)56-59
Number of pages4
JournalTerapevticheskii Arkhiv
Volume73
Issue number8
Publication statusPublished - 2001

Keywords

  • Adalat SL
  • Coronary artery bypass surgery
  • Late postoperative terms
  • One-photon emission computed tomography of the myocardium with 99m-TC (MIBI)

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism

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