Abstract
Fully loaded: Readily accessible and shelf-stable 1-bismuth(III) acetylides react rapidly and regiospecifically with organic azides in the presence of a copper(I) catalyst (see scheme). The reaction tolerates many functional groups and gives excellent yields of the previously unreported 5-bismuth triazolides. This uniquely reactive intermediate is functionalized under mild reaction conditions to give fully substituted 1,2,3-triazoles.
Original language | English |
---|---|
Pages (from-to) | 13037-13041 |
Number of pages | 5 |
Journal | Angewandte Chemie - International Edition |
Volume | 52 |
Issue number | 49 |
DOIs | |
Publication status | Published - 2 Dec 2013 |
Externally published | Yes |
Keywords
- bismuth
- click chemistry
- copper
- cycloaddition
- heterocycles
ASJC Scopus subject areas
- Chemistry(all)
- Catalysis