Abstract
(Chemical Equation Presented) Selective conversion, take three: Densely functionalized azetidine derivatives are formed in an experimentally simple three-component catalytic procedure through the highly selective reaction of readily available terminal alkynes under mild conditions (see scheme). The azetidinimine products are remarkably stable to a wide range of reaction conditions and readily undergo further functionalization.
| Original language | English |
|---|---|
| Pages (from-to) | 3157-3161 |
| Number of pages | 5 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 45 |
| Issue number | 19 |
| DOIs | |
| Publication status | Published - 5 May 2006 |
| Externally published | Yes |
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Keywords
- Alkynes
- Azides
- Cycloaddition
- Homogeneous catalysis
- Small ring systems
ASJC Scopus subject areas
- Chemistry(all)
Cite this
Copper-catalyzed reaction cascade : Direct conversion of alkynes into N-sulfonylazetidin-2-imines. / Whiting, Matthew; Fokin, Valery V.
In: Angewandte Chemie - International Edition, Vol. 45, No. 19, 05.05.2006, p. 3157-3161.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Copper-catalyzed reaction cascade
T2 - Direct conversion of alkynes into N-sulfonylazetidin-2-imines
AU - Whiting, Matthew
AU - Fokin, Valery V.
PY - 2006/5/5
Y1 - 2006/5/5
N2 - (Chemical Equation Presented) Selective conversion, take three: Densely functionalized azetidine derivatives are formed in an experimentally simple three-component catalytic procedure through the highly selective reaction of readily available terminal alkynes under mild conditions (see scheme). The azetidinimine products are remarkably stable to a wide range of reaction conditions and readily undergo further functionalization.
AB - (Chemical Equation Presented) Selective conversion, take three: Densely functionalized azetidine derivatives are formed in an experimentally simple three-component catalytic procedure through the highly selective reaction of readily available terminal alkynes under mild conditions (see scheme). The azetidinimine products are remarkably stable to a wide range of reaction conditions and readily undergo further functionalization.
KW - Alkynes
KW - Azides
KW - Cycloaddition
KW - Homogeneous catalysis
KW - Small ring systems
UR - http://www.scopus.com/inward/record.url?scp=33746187584&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33746187584&partnerID=8YFLogxK
U2 - 10.1002/anie.200503936
DO - 10.1002/anie.200503936
M3 - Article
C2 - 16570331
AN - SCOPUS:33746187584
VL - 45
SP - 3157
EP - 3161
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
SN - 1433-7851
IS - 19
ER -