Conditions of autonomic reciprocal interplay versus autonomic co-activation: Effects on non-linear heart rate dynamics

Laurent Mourot, Malika Bouhaddi, Emmanuel Gandelin, Sylvie Cappelle, Nhu Uyen Nguyen, Jean Pierre Wolf, Jean Denis Rouillon, Richard Hughson, Jacques Regnard

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22 Citations (Scopus)

Abstract

The present study was aimed at investigating the autonomic nervous system influences on the fractal organization of human heart rate during sympathovagal interactions, with special emphasize on the short-term fractal organization in heart rate variability (HRV), as assessed by the scaling exponent (α1) of the detrended fluctuation analysis. Linear and non-linear HRV analyses were used to study the sympathetic and vagal modulation of heart rate in ten healthy men (mean ± SEM; age 26 ± 1 years) during conditions of 1) increased sympathetic activity and vagal withdrawal (head-up tilt), 2) decreased sympathetic activity and increased vagal outflow (thermoneutral upright head-out water immersion, WIn), and 3) simultaneous activation of the two arms of the autonomic nervous activity (upright head-out immersion in cold water, WIc). Hemodynamic and linear HRV results were consistent with previous reports during similar physiological conditions. α1 increased significantly during head-up tilt (from 0.71 ± 0.13 supine to 0.90 ± 0.15 upright) and WIn (0.86 ± 0.10) and was significantly decreased during WIc (0.61 ± 0.15). Thus, α1 increased when the cardiac autonomic interplay was altered in a reciprocal fashion, whatever the direction of the balance change. Conversely, α1 decreased during the concomitant activation of both vagal and sympathetic activities. The results of linear analysis were necessary to precisely define the direction of change in autonomic control revealed by an increase in α1, while the direction of change in α1 indicated whether an increased vagal activity is coupled with a decreased or increased sympathetic activation. Using both linear and non-linear analysis of HRV may increase the understanding of changes in cardiac autonomic status.

Original languageEnglish
Pages (from-to)27-36
Number of pages10
JournalAutonomic Neuroscience: Basic and Clinical
Volume137
Issue number1-2
DOIs
Publication statusPublished - 30 Dec 2007
Externally publishedYes

Keywords

  • Cold
  • Detrended fluctuation analysis
  • Head-out water immersion
  • Head-up tilt
  • Spectral analysis

ASJC Scopus subject areas

  • Endocrine and Autonomic Systems
  • Clinical Neurology
  • Cellular and Molecular Neuroscience

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  • Cite this

    Mourot, L., Bouhaddi, M., Gandelin, E., Cappelle, S., Nguyen, N. U., Wolf, J. P., Rouillon, J. D., Hughson, R., & Regnard, J. (2007). Conditions of autonomic reciprocal interplay versus autonomic co-activation: Effects on non-linear heart rate dynamics. Autonomic Neuroscience: Basic and Clinical, 137(1-2), 27-36. https://doi.org/10.1016/j.autneu.2007.06.284