Data on volume of the intracellular compartment where the internalized toxin is located and toxin concentration in this compartment have been obtained. Suggestions have been made about a role of toxin molecule aggregates in the translocation of A-chain into cytosol, which leads to cell death.
- confocal microscopy
- monoclonal antibodies
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Environmental Science(all)