Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin

Sh Yu Khapchaev, S. S. Gutor, I. P. Kaminskii, E. E. Kremer, S. V. Krivoshchekov, I. V. Mil'to, Alexandra Gennadievna Pershina, I. V. Petrova, I. V. Saltykova, N. S. Subbotina, K. V. Khvorilova

Research output: Contribution to journal › Article

Abstract

Data on volume of the intracellular compartment where the internalized toxin is located and toxin concentration in this compartment have been obtained. Suggestions have been made about a role of toxin molecule aggregates in the translocation of A-chain into cytosol, which leads to cell death.

Original language	English
Pages (from-to)	174-177
Number of pages	4
Journal	Moscow University Biological Sciences Bulletin
Volume	68
Issue number	4
DOIs	https://doi.org/10.3103/S0096392514010040
Publication status	Published - Oct 2013
Externally published	Yes

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Keywords

confocal microscopy
monoclonal antibodies
ricin
viscumin

ASJC Scopus subject areas

Agricultural and Biological Sciences(all)
Biochemistry, Genetics and Molecular Biology(all)
Environmental Science(all)

Cite this

Khapchaev, S. Y., Gutor, S. S., Kaminskii, I. P., Kremer, E. E., Krivoshchekov, S. V., Mil'to, I. V., ... Khvorilova, K. V. (2013). Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin. Moscow University Biological Sciences Bulletin, 68(4), 174-177. https://doi.org/10.3103/S0096392514010040

Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin. / Khapchaev, Sh Yu; Gutor, S. S.; Kaminskii, I. P.; Kremer, E. E.; Krivoshchekov, S. V.; Mil'to, I. V.; Pershina, Alexandra Gennadievna; Petrova, I. V.; Saltykova, I. V.; Subbotina, N. S.; Khvorilova, K. V.

In: Moscow University Biological Sciences Bulletin, Vol. 68, No. 4, 10.2013, p. 174-177.

Research output: Contribution to journal › Article

Khapchaev, SY, Gutor, SS, Kaminskii, IP, Kremer, EE, Krivoshchekov, SV, Mil'to, IV, Pershina, AG, Petrova, IV, Saltykova, IV, Subbotina, NS & Khvorilova, KV 2013, 'Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin', Moscow University Biological Sciences Bulletin, vol. 68, no. 4, pp. 174-177. https://doi.org/10.3103/S0096392514010040

Khapchaev, Sh Yu ; Gutor, S. S. ; Kaminskii, I. P. ; Kremer, E. E. ; Krivoshchekov, S. V. ; Mil'to, I. V. ; Pershina, Alexandra Gennadievna ; Petrova, I. V. ; Saltykova, I. V. ; Subbotina, N. S. ; Khvorilova, K. V. / Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin. In: Moscow University Biological Sciences Bulletin. 2013 ; Vol. 68, No. 4. pp. 174-177.

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10.3103/S0096392514010040