Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin

Sh Yu Khapchaev, S. S. Gutor, I. P. Kaminskii, E. E. Kremer, S. V. Krivoshchekov, I. V. Mil'to, Alexandra Gennadievna Pershina, I. V. Petrova, I. V. Saltykova, N. S. Subbotina, K. V. Khvorilova

Research output: Contribution to journalArticle

Abstract

Data on volume of the intracellular compartment where the internalized toxin is located and toxin concentration in this compartment have been obtained. Suggestions have been made about a role of toxin molecule aggregates in the translocation of A-chain into cytosol, which leads to cell death.

Original languageEnglish
Pages (from-to)174-177
Number of pages4
JournalMoscow University Biological Sciences Bulletin
Volume68
Issue number4
DOIs
Publication statusPublished - Oct 2013
Externally publishedYes

Fingerprint

ricin
Ricin
Cell death
Cytosol
toxin
Cell Death
toxins
Molecules
cells
cell aggregates
cytosol
translocation
cell death
mistletoe lectin I

Keywords

  • confocal microscopy
  • monoclonal antibodies
  • ricin
  • viscumin

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Environmental Science(all)

Cite this

Khapchaev, S. Y., Gutor, S. S., Kaminskii, I. P., Kremer, E. E., Krivoshchekov, S. V., Mil'to, I. V., ... Khvorilova, K. V. (2013). Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin. Moscow University Biological Sciences Bulletin, 68(4), 174-177. https://doi.org/10.3103/S0096392514010040

Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin. / Khapchaev, Sh Yu; Gutor, S. S.; Kaminskii, I. P.; Kremer, E. E.; Krivoshchekov, S. V.; Mil'to, I. V.; Pershina, Alexandra Gennadievna; Petrova, I. V.; Saltykova, I. V.; Subbotina, N. S.; Khvorilova, K. V.

In: Moscow University Biological Sciences Bulletin, Vol. 68, No. 4, 10.2013, p. 174-177.

Research output: Contribution to journalArticle

Khapchaev, SY, Gutor, SS, Kaminskii, IP, Kremer, EE, Krivoshchekov, SV, Mil'to, IV, Pershina, AG, Petrova, IV, Saltykova, IV, Subbotina, NS & Khvorilova, KV 2013, 'Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin', Moscow University Biological Sciences Bulletin, vol. 68, no. 4, pp. 174-177. https://doi.org/10.3103/S0096392514010040
Khapchaev, Sh Yu ; Gutor, S. S. ; Kaminskii, I. P. ; Kremer, E. E. ; Krivoshchekov, S. V. ; Mil'to, I. V. ; Pershina, Alexandra Gennadievna ; Petrova, I. V. ; Saltykova, I. V. ; Subbotina, N. S. ; Khvorilova, K. V. / Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin. In: Moscow University Biological Sciences Bulletin. 2013 ; Vol. 68, No. 4. pp. 174-177.
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