Abstract
Data on volume of the intracellular compartment where the internalized toxin is located and toxin concentration in this compartment have been obtained. Suggestions have been made about a role of toxin molecule aggregates in the translocation of A-chain into cytosol, which leads to cell death.
| Original language | English |
|---|---|
| Pages (from-to) | 174-177 |
| Number of pages | 4 |
| Journal | Moscow University Biological Sciences Bulletin |
| Volume | 68 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Oct 2013 |
| Externally published | Yes |
Keywords
- confocal microscopy
- monoclonal antibodies
- ricin
- viscumin
ASJC Scopus subject areas
- Agricultural and Biological Sciences(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Environmental Science(all)
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Khapchaev, S. Y., Gutor, S. S., Kaminskii, I. P., Kremer, E. E., Krivoshchekov, S. V., Mil'to, I. V., Pershina, A. G., Petrova, I. V., Saltykova, I. V., Subbotina, N. S., & Khvorilova, K. V. (2013). Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin. Moscow University Biological Sciences Bulletin, 68(4), 174-177. https://doi.org/10.3103/S0096392514010040