Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin

Abstract

Data on volume of the intracellular compartment where the internalized toxin is located and toxin concentration in this compartment have been obtained. Suggestions have been made about a role of toxin molecule aggregates in the translocation of A-chain into cytosol, which leads to cell death.

Original language	English
Pages (from-to)	174-177
Number of pages	4
Journal	Moscow University Biological Sciences Bulletin
Volume	68
Issue number	4
DOIs	https://doi.org/10.3103/S0096392514010040
Publication status	Published - Oct 2013
Externally published	Yes

Keywords

confocal microscopy
monoclonal antibodies
ricin
viscumin

ASJC Scopus subject areas

Agricultural and Biological Sciences(all)
Biochemistry, Genetics and Molecular Biology(all)
Environmental Science(all)

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10.3103/S0096392514010040

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Khapchaev, S. Y., Gutor, S. S., Kaminskii, I. P., Kremer, E. E., Krivoshchekov, S. V., Mil'to, I. V., Pershina, A. G., Petrova, I. V., Saltykova, I. V., Subbotina, N. S., & Khvorilova, K. V. (2013). Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin. Moscow University Biological Sciences Bulletin, 68(4), 174-177. https://doi.org/10.3103/S0096392514010040

Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin. / Khapchaev, Sh Yu; Gutor, S. S.; Kaminskii, I. P.; Kremer, E. E.; Krivoshchekov, S. V.; Mil'to, I. V.; Pershina, Alexandra Gennadievna; Petrova, I. V.; Saltykova, I. V.; Subbotina, N. S.; Khvorilova, K. V.

In: Moscow University Biological Sciences Bulletin, Vol. 68, No. 4, 10.2013, p. 174-177.

Research output: Contribution to journal › Article › peer-review

Khapchaev, SY, Gutor, SS, Kaminskii, IP, Kremer, EE, Krivoshchekov, SV, Mil'to, IV, Pershina, AG, Petrova, IV, Saltykova, IV, Subbotina, NS & Khvorilova, KV 2013, 'Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin', Moscow University Biological Sciences Bulletin, vol. 68, no. 4, pp. 174-177. https://doi.org/10.3103/S0096392514010040

Khapchaev, Sh Yu ; Gutor, S. S. ; Kaminskii, I. P. ; Kremer, E. E. ; Krivoshchekov, S. V. ; Mil'to, I. V. ; Pershina, Alexandra Gennadievna ; Petrova, I. V. ; Saltykova, I. V. ; Subbotina, N. S. ; Khvorilova, K. V. / Concentration of toxins in endosomal compartment of the cells pretreated with ricin and viscumin. In: Moscow University Biological Sciences Bulletin. 2013 ; Vol. 68, No. 4. pp. 174-177.

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abstract = "Data on volume of the intracellular compartment where the internalized toxin is located and toxin concentration in this compartment have been obtained. Suggestions have been made about a role of toxin molecule aggregates in the translocation of A-chain into cytosol, which leads to cell death.",

keywords = "confocal microscopy, monoclonal antibodies, ricin, viscumin",

author = "Khapchaev, {Sh Yu} and Gutor, {S. S.} and Kaminskii, {I. P.} and Kremer, {E. E.} and Krivoshchekov, {S. V.} and Mil'to, {I. V.} and Pershina, {Alexandra Gennadievna} and Petrova, {I. V.} and Saltykova, {I. V.} and Subbotina, {N. S.} and Khvorilova, {K. V.}",

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AU - Kremer, E. E.

AU - Krivoshchekov, S. V.

AU - Mil'to, I. V.

AU - Pershina, Alexandra Gennadievna

AU - Petrova, I. V.

AU - Saltykova, I. V.

AU - Subbotina, N. S.

AU - Khvorilova, K. V.

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KW - confocal microscopy

KW - monoclonal antibodies

KW - ricin

KW - viscumin

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