Comparative assessment of single-photon emission computed tomography with 99mTc-MIBI for predicting the course of ischemic heart disease in patients with cardiosclerosis followed to myocardial infarction

V. I. Chernov, S. M. Salpagarova, Yu I. Zyablov, Zh V. Vesnina, Yu B. Lishmanov

Research output: Contribution to journalArticle


Methodical approaches to quantitative techniques in the use of 99mTc-MIBI SPECT for predicting the outcome of disease in patients after acute myocardial infarction (AMI) are developed. The 99mTc-MIBI SPECT method was applied in 155 patients with ischemic hearth disease (IHD) following to AMI. Concurrently, echocardiography and the bicycle test were used. The extension of perfusion defects a level of uptake of the indicator in those areas and the aggregated perfusion defect index were determined in all patients. The best predictors of the unfavorable course of disease in patients with the history of AMI were extensive perfusion defects at rest and at the peak of the adenosine test. The parameters provided by echocardiography, the bicycle exercise and other studies did not enhance the prognostic value of information provided by 99mTc-MIBI SPECT.

Original languageEnglish
Pages (from-to)40-44
Number of pages5
JournalMeditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'
Issue number1
Publication statusPublished - 2002



  • Ischemic heart disease
  • Myocardial infarction
  • Myocardial scintigraphy
  • Postinfarction cardiosclerosis
  • Prognosis
  • The Tc methoxy isobutyl isonitrile (Tc-MIBI)

ASJC Scopus subject areas

  • Nuclear Energy and Engineering

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