Comparative assessment of single-photon emission computed tomography with <sup>99m</sup>Tc-MIBI for predicting the course of ischemic heart disease in patients with cardiosclerosis followed to myocardial infarction

Abstract

Methodical approaches to quantitative techniques in the use of ^99mTc-MIBI SPECT for predicting the outcome of disease in patients after acute myocardial infarction (AMI) are developed. The ^99mTc-MIBI SPECT method was applied in 155 patients with ischemic hearth disease (IHD) following to AMI. Concurrently, echocardiography and the bicycle test were used. The extension of perfusion defects a level of uptake of the indicator in those areas and the aggregated perfusion defect index were determined in all patients. The best predictors of the unfavorable course of disease in patients with the history of AMI were extensive perfusion defects at rest and at the peak of the adenosine test. The parameters provided by echocardiography, the bicycle exercise and other studies did not enhance the prognostic value of information provided by ^99mTc-MIBI SPECT.

Original language	English
Pages (from-to)	40-44
Number of pages	5
Journal	Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'
Volume	47
Issue number	1
Publication status	Published - 2002

Keywords

Ischemic heart disease
Myocardial infarction
Myocardial scintigraphy
Postinfarction cardiosclerosis
Prognosis
The Tc methoxy isobutyl isonitrile (Tc-MIBI)

ASJC Scopus subject areas

Nuclear Energy and Engineering

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Chernov, V. I., Salpagarova, S. M., Zyablov, Y. I., Vesnina, Z. V., & Lishmanov, Y. B. (2002). Comparative assessment of single-photon emission computed tomography with ^99mTc-MIBI for predicting the course of ischemic heart disease in patients with cardiosclerosis followed to myocardial infarction. Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost', 47(1), 40-44.

Comparative assessment of single-photon emission computed tomography with ^99mTc-MIBI for predicting the course of ischemic heart disease in patients with cardiosclerosis followed to myocardial infarction. / Chernov, V. I.; Salpagarova, S. M.; Zyablov, Yu I.; Vesnina, Zh V.; Lishmanov, Yu B.

In: Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost', Vol. 47, No. 1, 2002, p. 40-44.

Research output: Contribution to journal › Article › peer-review

Chernov, V. I. ; Salpagarova, S. M. ; Zyablov, Yu I. ; Vesnina, Zh V. ; Lishmanov, Yu B. / Comparative assessment of single-photon emission computed tomography with ^99mTc-MIBI for predicting the course of ischemic heart disease in patients with cardiosclerosis followed to myocardial infarction. In: Meditsinskaya Radiologiya I Radiatsionnaya Bezopasnost'. 2002 ; Vol. 47, No. 1. pp. 40-44.

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abstract = "Methodical approaches to quantitative techniques in the use of 99mTc-MIBI SPECT for predicting the outcome of disease in patients after acute myocardial infarction (AMI) are developed. The 99mTc-MIBI SPECT method was applied in 155 patients with ischemic hearth disease (IHD) following to AMI. Concurrently, echocardiography and the bicycle test were used. The extension of perfusion defects a level of uptake of the indicator in those areas and the aggregated perfusion defect index were determined in all patients. The best predictors of the unfavorable course of disease in patients with the history of AMI were extensive perfusion defects at rest and at the peak of the adenosine test. The parameters provided by echocardiography, the bicycle exercise and other studies did not enhance the prognostic value of information provided by 99mTc-MIBI SPECT.",

keywords = "Ischemic heart disease, Myocardial infarction, Myocardial scintigraphy, Postinfarction cardiosclerosis, Prognosis, The Tc methoxy isobutyl isonitrile (Tc-MIBI)",

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AU - Chernov, V. I.

AU - Salpagarova, S. M.

AU - Zyablov, Yu I.

AU - Vesnina, Zh V.

AU - Lishmanov, Yu B.

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N2 - Methodical approaches to quantitative techniques in the use of 99mTc-MIBI SPECT for predicting the outcome of disease in patients after acute myocardial infarction (AMI) are developed. The 99mTc-MIBI SPECT method was applied in 155 patients with ischemic hearth disease (IHD) following to AMI. Concurrently, echocardiography and the bicycle test were used. The extension of perfusion defects a level of uptake of the indicator in those areas and the aggregated perfusion defect index were determined in all patients. The best predictors of the unfavorable course of disease in patients with the history of AMI were extensive perfusion defects at rest and at the peak of the adenosine test. The parameters provided by echocardiography, the bicycle exercise and other studies did not enhance the prognostic value of information provided by 99mTc-MIBI SPECT.

AB - Methodical approaches to quantitative techniques in the use of 99mTc-MIBI SPECT for predicting the outcome of disease in patients after acute myocardial infarction (AMI) are developed. The 99mTc-MIBI SPECT method was applied in 155 patients with ischemic hearth disease (IHD) following to AMI. Concurrently, echocardiography and the bicycle test were used. The extension of perfusion defects a level of uptake of the indicator in those areas and the aggregated perfusion defect index were determined in all patients. The best predictors of the unfavorable course of disease in patients with the history of AMI were extensive perfusion defects at rest and at the peak of the adenosine test. The parameters provided by echocardiography, the bicycle exercise and other studies did not enhance the prognostic value of information provided by 99mTc-MIBI SPECT.

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KW - The Tc methoxy isobutyl isonitrile (Tc-MIBI)

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