Between March 2003 and February 2005 cell therapy with mononuclear bone marrow cells (MBMC) was used in 38 and 4 patients with ischemic heart disease and dilated cardiomyopathy, respectively. Intracardiac administration of MBMC (87±12 millions) was carried out during coronary artery bypass surgery and/or left ventricular aneurism resection (n=25) or in cardiac catheterization laboratory (n=17). For verification of cells fixation they were labeled with "Ceretec" 99mTc-HMPAO. Accumulation of labeled cells after 24 hours was 1.6±0.001%. After 6 months parameters of intracardiac hemodynamics and transitory myocardial perfusion defects improved significantly in all patients with ischemic heart disease.
|Number of pages||5|
|Publication status||Published - 2006|
- Cell therapy
- Cellular cardiomyoplasty
- Heart failure, treatment
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine