Abstract
Purpose: Comparison of the dosimetric accuracy of the enhanced collapsed cone (eCC) algorithm with the commercially avail-able Monte Carlo (MC) dose calculation for complex treatment techniques. Material and Methods: A total of 8 intensity-modulated radiotherapy (IMRT) and 2 stereotactic body radiotherapy (SBRT) lung cases were calculated with eCC and MC algorithms with the treatment planning systems (TPS) Oncentra MasterPlan 3.2 (Nucle-tron) and Monaco 2.01 (Elekta/CMS). Fluence optimization as well as sequencing of IMRT plans was primarily performed us-ing Monaco. Dose prediction errors were calculated using MC as reference. The dose-volume histrogram (DVH) analysis was complemented with 2D and 3D gamma evaluation. Both algorithms were compared to measurements using the Delta4 system (Scandidos). Results: Recalculated with eCC IMRT plans resulted in lower planned target volume (PTV) coverage, as well as in lower organs-at-risk (OAR) doses up to 8%. Small deviations between MC and eCC in PTV dose (1-2%) were detected for IMRT cases, while larger deviations were observed for SBRT (up to 5%). Conformity indices of both calculations were similar; however, the homogeneity of the eCC calculated plans was slightly better. Delta4 measurements confirmed high dosimetric accuracy of both TPS. Conclusion: Mean dose prediction errors < 3% for PTV suggest that both algorithms enable highly accurate dose calculations under clinical conditions. However, users should be aware of slightly underestimated OAR doses using the eCC algorithm.
| Original language | English |
|---|---|
| Pages (from-to) | 433-441 |
| Number of pages | 9 |
| Journal | Strahlentherapie und Onkologie |
| Volume | 187 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Jul 2011 |
| Externally published | Yes |
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Keywords
- Collapsed cone algorithm
- Dose calculation
- IMRT
- Monte Carlo
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Oncology
Cite this
Clinical comparison of dose calculation using the enhanced collapsed cone algorithm vs. a new Monte Carlo algorithm. / Fotina, Irina; Kragl, Gabriele; Kroupa, Bernhard; Trausmuth, Robert; Georg, Dietmar.
In: Strahlentherapie und Onkologie, Vol. 187, No. 7, 07.2011, p. 433-441.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Clinical comparison of dose calculation using the enhanced collapsed cone algorithm vs. a new Monte Carlo algorithm
AU - Fotina, Irina
AU - Kragl, Gabriele
AU - Kroupa, Bernhard
AU - Trausmuth, Robert
AU - Georg, Dietmar
PY - 2011/7
Y1 - 2011/7
N2 - Purpose: Comparison of the dosimetric accuracy of the enhanced collapsed cone (eCC) algorithm with the commercially avail-able Monte Carlo (MC) dose calculation for complex treatment techniques. Material and Methods: A total of 8 intensity-modulated radiotherapy (IMRT) and 2 stereotactic body radiotherapy (SBRT) lung cases were calculated with eCC and MC algorithms with the treatment planning systems (TPS) Oncentra MasterPlan 3.2 (Nucle-tron) and Monaco 2.01 (Elekta/CMS). Fluence optimization as well as sequencing of IMRT plans was primarily performed us-ing Monaco. Dose prediction errors were calculated using MC as reference. The dose-volume histrogram (DVH) analysis was complemented with 2D and 3D gamma evaluation. Both algorithms were compared to measurements using the Delta4 system (Scandidos). Results: Recalculated with eCC IMRT plans resulted in lower planned target volume (PTV) coverage, as well as in lower organs-at-risk (OAR) doses up to 8%. Small deviations between MC and eCC in PTV dose (1-2%) were detected for IMRT cases, while larger deviations were observed for SBRT (up to 5%). Conformity indices of both calculations were similar; however, the homogeneity of the eCC calculated plans was slightly better. Delta4 measurements confirmed high dosimetric accuracy of both TPS. Conclusion: Mean dose prediction errors < 3% for PTV suggest that both algorithms enable highly accurate dose calculations under clinical conditions. However, users should be aware of slightly underestimated OAR doses using the eCC algorithm.
AB - Purpose: Comparison of the dosimetric accuracy of the enhanced collapsed cone (eCC) algorithm with the commercially avail-able Monte Carlo (MC) dose calculation for complex treatment techniques. Material and Methods: A total of 8 intensity-modulated radiotherapy (IMRT) and 2 stereotactic body radiotherapy (SBRT) lung cases were calculated with eCC and MC algorithms with the treatment planning systems (TPS) Oncentra MasterPlan 3.2 (Nucle-tron) and Monaco 2.01 (Elekta/CMS). Fluence optimization as well as sequencing of IMRT plans was primarily performed us-ing Monaco. Dose prediction errors were calculated using MC as reference. The dose-volume histrogram (DVH) analysis was complemented with 2D and 3D gamma evaluation. Both algorithms were compared to measurements using the Delta4 system (Scandidos). Results: Recalculated with eCC IMRT plans resulted in lower planned target volume (PTV) coverage, as well as in lower organs-at-risk (OAR) doses up to 8%. Small deviations between MC and eCC in PTV dose (1-2%) were detected for IMRT cases, while larger deviations were observed for SBRT (up to 5%). Conformity indices of both calculations were similar; however, the homogeneity of the eCC calculated plans was slightly better. Delta4 measurements confirmed high dosimetric accuracy of both TPS. Conclusion: Mean dose prediction errors < 3% for PTV suggest that both algorithms enable highly accurate dose calculations under clinical conditions. However, users should be aware of slightly underestimated OAR doses using the eCC algorithm.
KW - Collapsed cone algorithm
KW - Dose calculation
KW - IMRT
KW - Monte Carlo
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UR - http://www.scopus.com/inward/citedby.url?scp=80052081268&partnerID=8YFLogxK
U2 - 10.1007/s00066-011-2215-9
DO - 10.1007/s00066-011-2215-9
M3 - Article
VL - 187
SP - 433
EP - 441
JO - Strahlentherapie und Onkologie
JF - Strahlentherapie und Onkologie
SN - 0179-7158
IS - 7
ER -