Abstract
Anti-inflammatory activity of amides of levopimaric acid (LpA) with acetylenic moiety and its esters with 4-R-triazolic substitutions was investigated using histamine-induced mice paw edema model. The synthesized LpA derivatives possess anti-inflammatory activity comparable to the activity of indomethacin.
Original language | English |
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Pages (from-to) | 145-157 |
Number of pages | 13 |
Journal | Arkivoc |
Volume | 2014 |
Issue number | 5 |
DOIs | |
Publication status | Published - 19 Jul 2014 |
Externally published | Yes |
Keywords
- 1,2,3-triazole
- Acetylenes
- Antiinflammatory activity
- Click Chemistry
- Diterpenoids
- Levopimaric acid
ASJC Scopus subject areas
- Organic Chemistry