Chemical composition and biological activity of a fraction of meadowsweet extract

I. V. Shilova, A. A. Semenov, N. I. Suslov, E. I. Korotkova, Anna Nikolaevna Vtorushina, V. V. Belyakova

Research output: Contribution to journal › Article

Abstract

Studies of the chemical composition of a butanol fraction of an extract from the above-ground part of the meadowsweet in 70% ethanol yielded five substances which were flavonoids (quercetin, isoquercetin, quercetin 4?-glucoside, rutin) and phenolcarboxylic acids (gallic acid). The fraction was found to have nootropic actions, with antiamnestic, antihypoxic, antioxidant, and adaptogenic activities. Studies of the antioxidant properties of the individual compounds showed that isoquercetin, quercetin 4?-glucoside, and rutin were more active than dihydroquercetin and ascorbic acid.

Original language	English
Pages (from-to)	185-190
Number of pages	6
Journal	Pharmaceutical Chemistry Journal
Volume	43
Issue number	4
DOIs	https://doi.org/10.1007/s11094-009-0275-2
Publication status	Published - Apr 2009

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Keywords

Antioxidant activity
Meadowsweet
Nootropic activity
Phenol compounds

ASJC Scopus subject areas

Drug Discovery
Pharmacology

Cite this

Shilova, I. V., Semenov, A. A., Suslov, N. I., Korotkova, E. I., Vtorushina, A. N., & Belyakova, V. V. (2009). Chemical composition and biological activity of a fraction of meadowsweet extract. Pharmaceutical Chemistry Journal, 43(4), 185-190. https://doi.org/10.1007/s11094-009-0275-2

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AU - Shilova, I. V.

AU - Semenov, A. A.

AU - Suslov, N. I.

AU - Korotkova, E. I.

AU - Vtorushina, Anna Nikolaevna

AU - Belyakova, V. V.

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10.1007/s11094-009-0275-2