Abstract
Studies of the chemical composition of a butanol fraction of an extract from the above-ground part of the meadowsweet in 70% ethanol yielded five substances which were flavonoids (quercetin, isoquercetin, quercetin 4?-glucoside, rutin) and phenolcarboxylic acids (gallic acid). The fraction was found to have nootropic actions, with antiamnestic, antihypoxic, antioxidant, and adaptogenic activities. Studies of the antioxidant properties of the individual compounds showed that isoquercetin, quercetin 4?-glucoside, and rutin were more active than dihydroquercetin and ascorbic acid.
| Original language | English |
|---|---|
| Pages (from-to) | 185-190 |
| Number of pages | 6 |
| Journal | Pharmaceutical Chemistry Journal |
| Volume | 43 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 2009 |
Keywords
- Antioxidant activity
- Meadowsweet
- Nootropic activity
- Phenol compounds
ASJC Scopus subject areas
- Drug Discovery
- Pharmacology
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Shilova, I. V., Semenov, A. A., Suslov, N. I., Korotkova, E. I., Vtorushina, A. N., & Belyakova, V. V. (2009). Chemical composition and biological activity of a fraction of meadowsweet extract. Pharmaceutical Chemistry Journal, 43(4), 185-190. https://doi.org/10.1007/s11094-009-0275-2