Abstract
Studies of the chemical composition of a butanol fraction of an extract from the above-ground part of the meadowsweet in 70% ethanol yielded five substances which were flavonoids (quercetin, isoquercetin, quercetin 4?-glucoside, rutin) and phenolcarboxylic acids (gallic acid). The fraction was found to have nootropic actions, with antiamnestic, antihypoxic, antioxidant, and adaptogenic activities. Studies of the antioxidant properties of the individual compounds showed that isoquercetin, quercetin 4?-glucoside, and rutin were more active than dihydroquercetin and ascorbic acid.
| Original language | English |
|---|---|
| Pages (from-to) | 185-190 |
| Number of pages | 6 |
| Journal | Pharmaceutical Chemistry Journal |
| Volume | 43 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 2009 |
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Keywords
- Antioxidant activity
- Meadowsweet
- Nootropic activity
- Phenol compounds
ASJC Scopus subject areas
- Drug Discovery
- Pharmacology
Cite this
Chemical composition and biological activity of a fraction of meadowsweet extract. / Shilova, I. V.; Semenov, A. A.; Suslov, N. I.; Korotkova, E. I.; Vtorushina, Anna Nikolaevna; Belyakova, V. V.
In: Pharmaceutical Chemistry Journal, Vol. 43, No. 4, 04.2009, p. 185-190.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Chemical composition and biological activity of a fraction of meadowsweet extract
AU - Shilova, I. V.
AU - Semenov, A. A.
AU - Suslov, N. I.
AU - Korotkova, E. I.
AU - Vtorushina, Anna Nikolaevna
AU - Belyakova, V. V.
PY - 2009/4
Y1 - 2009/4
N2 - Studies of the chemical composition of a butanol fraction of an extract from the above-ground part of the meadowsweet in 70% ethanol yielded five substances which were flavonoids (quercetin, isoquercetin, quercetin 4?-glucoside, rutin) and phenolcarboxylic acids (gallic acid). The fraction was found to have nootropic actions, with antiamnestic, antihypoxic, antioxidant, and adaptogenic activities. Studies of the antioxidant properties of the individual compounds showed that isoquercetin, quercetin 4?-glucoside, and rutin were more active than dihydroquercetin and ascorbic acid.
AB - Studies of the chemical composition of a butanol fraction of an extract from the above-ground part of the meadowsweet in 70% ethanol yielded five substances which were flavonoids (quercetin, isoquercetin, quercetin 4?-glucoside, rutin) and phenolcarboxylic acids (gallic acid). The fraction was found to have nootropic actions, with antiamnestic, antihypoxic, antioxidant, and adaptogenic activities. Studies of the antioxidant properties of the individual compounds showed that isoquercetin, quercetin 4?-glucoside, and rutin were more active than dihydroquercetin and ascorbic acid.
KW - Antioxidant activity
KW - Meadowsweet
KW - Nootropic activity
KW - Phenol compounds
UR - http://www.scopus.com/inward/record.url?scp=69249209661&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=69249209661&partnerID=8YFLogxK
U2 - 10.1007/s11094-009-0275-2
DO - 10.1007/s11094-009-0275-2
M3 - Article
VL - 43
SP - 185
EP - 190
JO - Pharmaceutical Chemistry Journal
JF - Pharmaceutical Chemistry Journal
SN - 0091-150X
IS - 4
ER -