TY - JOUR
T1 - Characterization of electron beam deposited Nb2O5 coatings for biomedical applications
AU - Dinu, Mihaela
AU - Braic, Laurentiu
AU - Padmanabhan, Sibu C.
AU - Morris, Michael A.
AU - Titorencu, Irina
AU - Pruna, Vasile
AU - Parau, Anca
AU - Romanchikova, Nadezhda
AU - Petrik, Leslie F.
AU - Vladescu, Alina
PY - 2020/3
Y1 - 2020/3
N2 - Niobium oxide coatings deposited on Ti6Al4V substrates by electron beam deposition and annealed in air at 600 °C and 800 °C were evaluated for their suitability towards dental, maxillofacial or orthopaedic implant applications. A detailed physico-chemical properties investigation was carried out in order to determine their elemental and phase composition, surface morphology and roughness, mechanical properties, wettability, and corrosion resistance in simulated body fluid solution (pH = 7.4) at room temperature. The biocompatibility of the bare Ti6Al4V substrate and coated surfaces was evaluated by testing the cellular adhesion and viability/proliferation of human osteosarcoma cells (MG-63) after 72 h of incubation. The coatings annealed at 800 °C exhibit more phase pure nanocrystalline Nb2O5 surfaces with enhanced wettability, reduced porosity and enhanced corrosion resistance properties making them good candidate for dental, maxillofacial or orthopaedic implant applications.
AB - Niobium oxide coatings deposited on Ti6Al4V substrates by electron beam deposition and annealed in air at 600 °C and 800 °C were evaluated for their suitability towards dental, maxillofacial or orthopaedic implant applications. A detailed physico-chemical properties investigation was carried out in order to determine their elemental and phase composition, surface morphology and roughness, mechanical properties, wettability, and corrosion resistance in simulated body fluid solution (pH = 7.4) at room temperature. The biocompatibility of the bare Ti6Al4V substrate and coated surfaces was evaluated by testing the cellular adhesion and viability/proliferation of human osteosarcoma cells (MG-63) after 72 h of incubation. The coatings annealed at 800 °C exhibit more phase pure nanocrystalline Nb2O5 surfaces with enhanced wettability, reduced porosity and enhanced corrosion resistance properties making them good candidate for dental, maxillofacial or orthopaedic implant applications.
KW - Adhesion
KW - Annealed niobium oxide coatings
KW - Biocompatibility
KW - Corrosion resistance
KW - Electron beam deposition
KW - Hardness
KW - Reduced elastic modulus
KW - Tribological properties
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U2 - 10.1016/j.jmbbm.2019.103582
DO - 10.1016/j.jmbbm.2019.103582
M3 - Article
AN - SCOPUS:85076259117
VL - 103
JO - Journal of the Mechanical Behavior of Biomedical Materials
JF - Journal of the Mechanical Behavior of Biomedical Materials
SN - 1751-6161
M1 - 103582
ER -