Characterization of electron beam deposited Nb2O5 coatings for biomedical applications

Mihaela Dinu, Laurentiu Braic, Sibu C. Padmanabhan, Michael A. Morris, Irina Titorencu, Vasile Pruna, Anca Parau, Nadezhda Romanchikova, Leslie F. Petrik, Alina Vladescu

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Niobium oxide coatings deposited on Ti6Al4V substrates by electron beam deposition and annealed in air at 600 °C and 800 °C were evaluated for their suitability towards dental, maxillofacial or orthopaedic implant applications. A detailed physico-chemical properties investigation was carried out in order to determine their elemental and phase composition, surface morphology and roughness, mechanical properties, wettability, and corrosion resistance in simulated body fluid solution (pH = 7.4) at room temperature. The biocompatibility of the bare Ti6Al4V substrate and coated surfaces was evaluated by testing the cellular adhesion and viability/proliferation of human osteosarcoma cells (MG-63) after 72 h of incubation. The coatings annealed at 800 °C exhibit more phase pure nanocrystalline Nb2O5 surfaces with enhanced wettability, reduced porosity and enhanced corrosion resistance properties making them good candidate for dental, maxillofacial or orthopaedic implant applications.

Original languageEnglish
Article number103582
JournalJournal of the Mechanical Behavior of Biomedical Materials
Publication statusPublished - Mar 2020


  • Adhesion
  • Annealed niobium oxide coatings
  • Biocompatibility
  • Corrosion resistance
  • Electron beam deposition
  • Hardness
  • Reduced elastic modulus
  • Tribological properties

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Mechanics of Materials

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