Characterization of electron beam deposited Nb₂O₅ coatings for biomedical applications

Mihaela Dinu, Laurentiu Braic, Sibu C. Padmanabhan, Michael A. Morris, Irina Titorencu, Vasile Pruna, Anca Parau, Nadezhda Romanchikova, Leslie F. Petrik, Alina Vladescu

Research School of Chemistry & Applied Biomedical Sciences

Research output: Contribution to journal › Article

Abstract

Niobium oxide coatings deposited on Ti₆Al₄V substrates by electron beam deposition and annealed in air at 600 °C and 800 °C were evaluated for their suitability towards dental, maxillofacial or orthopaedic implant applications. A detailed physico-chemical properties investigation was carried out in order to determine their elemental and phase composition, surface morphology and roughness, mechanical properties, wettability, and corrosion resistance in simulated body fluid solution (pH = 7.4) at room temperature. The biocompatibility of the bare Ti₆Al₄V substrate and coated surfaces was evaluated by testing the cellular adhesion and viability/proliferation of human osteosarcoma cells (MG-63) after 72 h of incubation. The coatings annealed at 800 °C exhibit more phase pure nanocrystalline Nb₂O₅ surfaces with enhanced wettability, reduced porosity and enhanced corrosion resistance properties making them good candidate for dental, maxillofacial or orthopaedic implant applications.

Original language	English
Article number	103582
Journal	Journal of the Mechanical Behavior of Biomedical Materials
Volume	103
DOIs	https://doi.org/10.1016/j.jmbbm.2019.103582
Publication status	Published - Mar 2020

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Keywords

Adhesion
Annealed niobium oxide coatings
Biocompatibility
Corrosion resistance
Electron beam deposition
Hardness
Reduced elastic modulus
Tribological properties

ASJC Scopus subject areas

Biomaterials
Biomedical Engineering
Mechanics of Materials

Cite this

Dinu, M., Braic, L., Padmanabhan, S. C., Morris, M. A., Titorencu, I., Pruna, V., ... Vladescu, A. (2020). Characterization of electron beam deposited Nb₂O₅ coatings for biomedical applications. Journal of the Mechanical Behavior of Biomedical Materials, 103, [103582]. https://doi.org/10.1016/j.jmbbm.2019.103582

Characterization of electron beam deposited Nb₂O₅ coatings for biomedical applications. / Dinu, Mihaela; Braic, Laurentiu; Padmanabhan, Sibu C.; Morris, Michael A.; Titorencu, Irina; Pruna, Vasile; Parau, Anca; Romanchikova, Nadezhda; Petrik, Leslie F.; Vladescu, Alina.

In: Journal of the Mechanical Behavior of Biomedical Materials, Vol. 103, 103582, 03.2020.

Research output: Contribution to journal › Article

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abstract = "Niobium oxide coatings deposited on Ti6Al4V substrates by electron beam deposition and annealed in air at 600 °C and 800 °C were evaluated for their suitability towards dental, maxillofacial or orthopaedic implant applications. A detailed physico-chemical properties investigation was carried out in order to determine their elemental and phase composition, surface morphology and roughness, mechanical properties, wettability, and corrosion resistance in simulated body fluid solution (pH = 7.4) at room temperature. The biocompatibility of the bare Ti6Al4V substrate and coated surfaces was evaluated by testing the cellular adhesion and viability/proliferation of human osteosarcoma cells (MG-63) after 72 h of incubation. The coatings annealed at 800 °C exhibit more phase pure nanocrystalline Nb2O5 surfaces with enhanced wettability, reduced porosity and enhanced corrosion resistance properties making them good candidate for dental, maxillofacial or orthopaedic implant applications.",

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Access to Document

10.1016/j.jmbbm.2019.103582