Central κ1-opiate receptors and mechanisms of arrhythmogenesis

D. S. Ugdyzhekova, L. N. Maslov, Yu B. Lishmanov

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Agonists of κ1-opiate receptors injected in brain ventricle potentiate arrhythmogenic effect of adrenaline. Antagonist of κ1-opiate receptors norbinaltorphimine or ganglioblocker hexamethonium completely abolish proarrythmic effects of κ1-agonists. Norbinaltorphimine possesses intrinsic antiarrhythmic activity.

Original languageEnglish
Pages (from-to)571-573
Number of pages3
JournalBulletin of Experimental Biology and Medicine
Volume123
Issue number6
DOIs
Publication statusPublished - 1 Jan 1997

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Opioid Receptors
Hexamethonium
Epinephrine
Brain
norbinaltorphimine

Keywords

  • Arrhythmias
  • κ-opiate receptors

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

Central κ1-opiate receptors and mechanisms of arrhythmogenesis. / Ugdyzhekova, D. S.; Maslov, L. N.; Lishmanov, Yu B.

In: Bulletin of Experimental Biology and Medicine, Vol. 123, No. 6, 01.01.1997, p. 571-573.

Research output: Contribution to journalArticle

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