Abstract
Agonists of κ1-opiate receptors injected in brain ventricle potentiate arrhythmogenic effect of adrenaline. Antagonist of κ1-opiate receptors norbinaltorphimine or ganglioblocker hexamethonium completely abolish proarrythmic effects of κ1-agonists. Norbinaltorphimine possesses intrinsic antiarrhythmic activity.
Original language | English |
---|---|
Pages (from-to) | 571-573 |
Number of pages | 3 |
Journal | Bulletin of Experimental Biology and Medicine |
Volume | 123 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1 Jan 1997 |
Keywords
- Arrhythmias
- κ-opiate receptors
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)