Catalytic asymmetric C-H insertions of rhodium(II) azavinyl carbenes

Stepan Chuprakov, Jamal A. Malik, Mikhail Zibinsky, Valery V. Fokin

Research output: Contribution to journalArticle

144 Citations (Scopus)

Abstract

A highly efficient enantioselective C-H insertion of azavinyl carbenes into unactivated alkanes has been developed. These transition metal carbenes are directly generated from readily available and stable 1-sulfonyl-1,2,3-triazoles in the presence of chiral Rh(II) carboxylates and are used for C-H functionalization of alkanes to access a variety of β-chiral sulfonamides.

Original languageEnglish
Pages (from-to)10352-10355
Number of pages4
JournalJournal of the American Chemical Society
Volume133
Issue number27
DOIs
Publication statusPublished - 13 Jul 2011
Externally publishedYes

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ASJC Scopus subject areas

  • Chemistry(all)
  • Catalysis
  • Biochemistry
  • Colloid and Surface Chemistry

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