Cardiovascular rehabilitation increase arterial compliance in type 2 diabetic patients with coronary artery disease

L. Mourot, A. Boussuges, P. Campo, S. Maunier, X. Debussche, P. Blanc

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Aims: The effect of a cardiovascular rehabilitation program on arterial compliance in type 2 diabetes mellitus with coronary disease was studied. Methods: Hemodynamic data and arterial compliance were measured with a tonometer (HDI/Pulse wave CR-2000) in coronary artery disease patients with (n = 32) and without (n = 24) type 2 diabetes before and after a 6-week multidisciplinary cardiac rehabilitation program. Results: A decrease in heart rate and an increase in stroke volume without significant change in resting cardiac output were obtained in diabetic patients. Arterial compliance of both small and large arteries was significantly increased. In 10 diabetic patients, this increase could be related to an increase in the anti-hypertensive treatment and to the decreased blood pressure. In the 22 remainders, the small artery compliance was significantly increased independently of blood pressure change. Conclusions: Exercise training as well as optimization of diabetes and dyslipidemia treatment could explain the improvement of arterial compliance. If these changes are long-lasting and if they improve prognosis remains to be evaluated.

Original languageEnglish
Pages (from-to)138-144
Number of pages7
JournalDiabetes Research and Clinical Practice
Volume84
Issue number2
DOIs
Publication statusPublished - 1 May 2009
Externally publishedYes

Keywords

  • Arterial stiffness
  • Cardiac disease
  • Cardiovascular rehabilitation
  • Cardiovascular system
  • Exercise training
  • Tonometry
  • Type 2 diabetes mellitus

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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