Cardiovascular Effects of High-Molecular-Weight Compounds of Humic Nature

M. V. Zykova, M. V. Belousov, T. V. Lasukova, A. S. Gorbunov, L. A. Logvinova, A. M. Dygai

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

The active ingredient extracted from the peat humic substances was characterized by physicochemical parameters evaluated by UV- and IR-spectroscopy, titration, and elemental (C, H, N) analysis. The cardiovascular effects of this ingredient were examined on isolated Langendorff-perfused rat heart. It was found that the active substance in a concentration range of 0.01-0.1 mg/ml produced a vasodilating effect; in addition, it decreased the end-diastolic and left-ventricular developed pressures.

Original languageEnglish
Pages (from-to)206-209
Number of pages4
JournalBulletin of Experimental Biology and Medicine
Volume163
Issue number2
DOIs
Publication statusPublished - 1 Jun 2017

Keywords

  • cardiovascular effects
  • heart
  • humic acids
  • peat

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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