Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber

Abstract

We report on the employment of a biodegradable phosphate-based optical fiber as a pH sensing probe in physiological environment. The phosphate-based optical fiber preform was fabricated by the rod-in-tube technique. The fiber biodegradability was first tested in-vitro and then its biodegradability and toxicity were tested in-vivo. Optical probes for pH sensing were prepared by the immobilization of a fluorescent dye on the fiber tip by a sol-gel method. The fluorescence response of the pH-sensor was measured as a ratio of the emission intensities at the excitation wavelengths of 405 and 450 nm.

Original language	English
Title of host publication	Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII
Editors	Israel Gannot, Israel Gannot
Publisher	SPIE
ISBN (Electronic)	9781510614611
DOIs	https://doi.org/10.1117/12.2285148
Publication status	Published - 1 Jan 2018
Externally published	Yes
Event	Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII 2018 - San Francisco, United States Duration: 27 Jan 2018 → 28 Jan 2018

Publication series

Name	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	10488
ISSN (Print)	1605-7422

Conference

Conference	Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII 2018
Country	United States
City	San Francisco
Period	27.1.18 → 28.1.18

Keywords

biodegradable optical fiber
Biomaterials
optical fiber sensors

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Biomaterials
Radiology Nuclear Medicine and imaging

Access to Document

10.1117/12.2285148

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Cite this

Podrazký, O., Peterka, P., Vytykáčová, S., Proboštová, J., Kuneš, M., Lyutakov, O., Ceci-Ginistrelli, E., Pugliese, D., Boetti, N. G., Janner, D., & Milanese, D. (2018). Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber. In I. Gannot, & I. Gannot (Eds.), Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII [104880H] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10488). SPIE. https://doi.org/10.1117/12.2285148

Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber. / Podrazký, Ondřej; Peterka, Pavel; Vytykáčová, Soňa; Proboštová, Jana; Kuneš, Martin; Lyutakov, Oleksiy; Ceci-Ginistrelli, Edoardo; Pugliese, Diego; Boetti, Nadia G.; Janner, Davide; Milanese, Daniel.

Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII. ed. / Israel Gannot; Israel Gannot. SPIE, 2018. 104880H (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10488).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Podrazký, O, Peterka, P, Vytykáčová, S, Proboštová, J, Kuneš, M, Lyutakov, O, Ceci-Ginistrelli, E, Pugliese, D, Boetti, NG, Janner, D & Milanese, D 2018, Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber. in I Gannot & I Gannot (eds), Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII., 104880H, Progress in Biomedical Optics and Imaging - Proceedings of SPIE, vol. 10488, SPIE, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII 2018, San Francisco, United States, 27.1.18. https://doi.org/10.1117/12.2285148

Podrazký O, Peterka P, Vytykáčová S, Proboštová J, Kuneš M, Lyutakov O et al. Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber. In Gannot I, Gannot I, editors, Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII. SPIE. 2018. 104880H. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE). https://doi.org/10.1117/12.2285148

Podrazký, Ondřej ; Peterka, Pavel ; Vytykáčová, Soňa ; Proboštová, Jana ; Kuneš, Martin ; Lyutakov, Oleksiy ; Ceci-Ginistrelli, Edoardo ; Pugliese, Diego ; Boetti, Nadia G. ; Janner, Davide ; Milanese, Daniel. / Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber. Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII. editor / Israel Gannot ; Israel Gannot. SPIE, 2018. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE).

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