Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber

Ondřej Podrazký, Pavel Peterka, Soňa Vytykáčová, Jana Proboštová, Martin Kuneš, Oleksiy Lyutakov, Edoardo Ceci-Ginistrelli, Diego Pugliese, Nadia G. Boetti, Davide Janner, Daniel Milanese

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We report on the employment of a biodegradable phosphate-based optical fiber as a pH sensing probe in physiological environment. The phosphate-based optical fiber preform was fabricated by the rod-in-tube technique. The fiber biodegradability was first tested in-vitro and then its biodegradability and toxicity were tested in-vivo. Optical probes for pH sensing were prepared by the immobilization of a fluorescent dye on the fiber tip by a sol-gel method. The fluorescence response of the pH-sensor was measured as a ratio of the emission intensities at the excitation wavelengths of 405 and 450 nm.

Original languageEnglish
Title of host publicationOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII
EditorsIsrael Gannot, Israel Gannot
PublisherSPIE
ISBN (Electronic)9781510614611
DOIs
Publication statusPublished - 1 Jan 2018
Externally publishedYes
EventOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII 2018 - San Francisco, United States
Duration: 27 Jan 201828 Jan 2018

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume10488
ISSN (Print)1605-7422

Conference

ConferenceOptical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII 2018
CountryUnited States
CitySan Francisco
Period27.1.1828.1.18

Keywords

  • biodegradable optical fiber
  • Biomaterials
  • optical fiber sensors

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Podrazký, O., Peterka, P., Vytykáčová, S., Proboštová, J., Kuneš, M., Lyutakov, O., Ceci-Ginistrelli, E., Pugliese, D., Boetti, N. G., Janner, D., & Milanese, D. (2018). Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber. In I. Gannot, & I. Gannot (Eds.), Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII [104880H] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10488). SPIE. https://doi.org/10.1117/12.2285148