Abstract
We report on the employment of a biodegradable phosphate-based optical fiber as a pH sensing probe in physiological environment. The phosphate-based optical fiber preform was fabricated by the rod-in-tube technique. The fiber biodegradability was first tested in-vitro and then its biodegradability and toxicity were tested in-vivo. Optical probes for pH sensing were prepared by the immobilization of a fluorescent dye on the fiber tip by a sol-gel method. The fluorescence response of the pH-sensor was measured as a ratio of the emission intensities at the excitation wavelengths of 405 and 450 nm.
| Original language | English |
|---|---|
| Title of host publication | Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII |
| Editors | Israel Gannot, Israel Gannot |
| Publisher | SPIE |
| ISBN (Electronic) | 9781510614611 |
| DOIs | |
| Publication status | Published - 1 Jan 2018 |
| Externally published | Yes |
| Event | Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII 2018 - San Francisco, United States Duration: 27 Jan 2018 → 28 Jan 2018 |
Publication series
| Name | Progress in Biomedical Optics and Imaging - Proceedings of SPIE |
|---|---|
| Volume | 10488 |
| ISSN (Print) | 1605-7422 |
Conference
| Conference | Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII 2018 |
|---|---|
| Country | United States |
| City | San Francisco |
| Period | 27.1.18 → 28.1.18 |
Fingerprint
Keywords
- biodegradable optical fiber
- Biomaterials
- optical fiber sensors
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Atomic and Molecular Physics, and Optics
- Biomaterials
- Radiology Nuclear Medicine and imaging
Cite this
Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber. / Podrazký, Ondřej; Peterka, Pavel; Vytykáčová, Soňa; Proboštová, Jana; Kuneš, Martin; Lyutakov, Oleksiy; Ceci-Ginistrelli, Edoardo; Pugliese, Diego; Boetti, Nadia G.; Janner, Davide; Milanese, Daniel.
Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII. ed. / Israel Gannot; Israel Gannot. SPIE, 2018. 104880H (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 10488).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Biomedical and sensing applications of a multi-mode biodegradable phosphate-based optical fiber
AU - Podrazký, Ondřej
AU - Peterka, Pavel
AU - Vytykáčová, Soňa
AU - Proboštová, Jana
AU - Kuneš, Martin
AU - Lyutakov, Oleksiy
AU - Ceci-Ginistrelli, Edoardo
AU - Pugliese, Diego
AU - Boetti, Nadia G.
AU - Janner, Davide
AU - Milanese, Daniel
PY - 2018/1/1
Y1 - 2018/1/1
N2 - We report on the employment of a biodegradable phosphate-based optical fiber as a pH sensing probe in physiological environment. The phosphate-based optical fiber preform was fabricated by the rod-in-tube technique. The fiber biodegradability was first tested in-vitro and then its biodegradability and toxicity were tested in-vivo. Optical probes for pH sensing were prepared by the immobilization of a fluorescent dye on the fiber tip by a sol-gel method. The fluorescence response of the pH-sensor was measured as a ratio of the emission intensities at the excitation wavelengths of 405 and 450 nm.
AB - We report on the employment of a biodegradable phosphate-based optical fiber as a pH sensing probe in physiological environment. The phosphate-based optical fiber preform was fabricated by the rod-in-tube technique. The fiber biodegradability was first tested in-vitro and then its biodegradability and toxicity were tested in-vivo. Optical probes for pH sensing were prepared by the immobilization of a fluorescent dye on the fiber tip by a sol-gel method. The fluorescence response of the pH-sensor was measured as a ratio of the emission intensities at the excitation wavelengths of 405 and 450 nm.
KW - biodegradable optical fiber
KW - Biomaterials
KW - optical fiber sensors
UR - http://www.scopus.com/inward/record.url?scp=85046793796&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85046793796&partnerID=8YFLogxK
U2 - 10.1117/12.2285148
DO - 10.1117/12.2285148
M3 - Conference contribution
AN - SCOPUS:85046793796
T3 - Progress in Biomedical Optics and Imaging - Proceedings of SPIE
BT - Optical Fibers and Sensors for Medical Diagnostics and Treatment Applications XVIII
A2 - Gannot, Israel
A2 - Gannot, Israel
PB - SPIE
ER -