Biologically Active Substances From Dropwort (Filipendula vulgaris) and Assessment of Their Antioxidant Properties

Abstract

This study demonstrated the antioxidant activity of aqueous and aqueous-ethanolic (40%, 70%, 95%) extracts of the above-ground parts of the dropwort (Filipendula vulgaris Moench) in relation to the process of electroreduction of oxygen. Antioxidant properties were more marked in the more lipophilic dropwort extract. The lipophilic fraction of the aqueous extract (extracted with ethyl acetate) had marked antioxidant activity, and its efficacy was greater than those of dihydroquercetin and ascorbic acid, and this resulted from the more complete extraction of total biologically active compounds of phenolic (simple phenols, flavonoids, hydroxycoumarins, phenolcarboxylic acids) and triterpene (acids, saponins) nature, as well as amino acids.

Original language	English
Pages (from-to)	602-605
Number of pages	4
Journal	Pharmaceutical Chemistry Journal
Volume	51
Issue number	7
DOIs	https://doi.org/10.1007/s11094-017-1660-x
Publication status	Published - 1 Oct 2017

Keywords

cathodic voltammetry
Filipendula vulgaris Moench
phenolic and triterpene compounds

ASJC Scopus subject areas

Pharmacology
Drug Discovery

Access to Document

10.1007/s11094-017-1660-x

Fingerprint Dive into the research topics of 'Biologically Active Substances From Dropwort (Filipendula vulgaris) and Assessment of Their Antioxidant Properties'. Together they form a unique fingerprint.

Cite this

@article{85f65eac8d0c47a19879b7084062b18c,

title = "Biologically Active Substances From Dropwort (Filipendula vulgaris) and Assessment of Their Antioxidant Properties",

abstract = "This study demonstrated the antioxidant activity of aqueous and aqueous-ethanolic (40%, 70%, 95%) extracts of the above-ground parts of the dropwort (Filipendula vulgaris Moench) in relation to the process of electroreduction of oxygen. Antioxidant properties were more marked in the more lipophilic dropwort extract. The lipophilic fraction of the aqueous extract (extracted with ethyl acetate) had marked antioxidant activity, and its efficacy was greater than those of dihydroquercetin and ascorbic acid, and this resulted from the more complete extraction of total biologically active compounds of phenolic (simple phenols, flavonoids, hydroxycoumarins, phenolcarboxylic acids) and triterpene (acids, saponins) nature, as well as amino acids.",

keywords = "cathodic voltammetry, Filipendula vulgaris Moench, phenolic and triterpene compounds",

author = "Shilova, {I. V.} and Korotkova, {E. I.}",

year = "2017",

month = oct,

day = "1",

doi = "10.1007/s11094-017-1660-x",

language = "English",

volume = "51",

pages = "602--605",

journal = "Pharmaceutical Chemistry Journal",

issn = "0091-150X",

publisher = "Springer New York",

number = "7",

}

TY - JOUR

T1 - Biologically Active Substances From Dropwort (Filipendula vulgaris) and Assessment of Their Antioxidant Properties

AU - Shilova, I. V.

AU - Korotkova, E. I.

PY - 2017/10/1

Y1 - 2017/10/1

N2 - This study demonstrated the antioxidant activity of aqueous and aqueous-ethanolic (40%, 70%, 95%) extracts of the above-ground parts of the dropwort (Filipendula vulgaris Moench) in relation to the process of electroreduction of oxygen. Antioxidant properties were more marked in the more lipophilic dropwort extract. The lipophilic fraction of the aqueous extract (extracted with ethyl acetate) had marked antioxidant activity, and its efficacy was greater than those of dihydroquercetin and ascorbic acid, and this resulted from the more complete extraction of total biologically active compounds of phenolic (simple phenols, flavonoids, hydroxycoumarins, phenolcarboxylic acids) and triterpene (acids, saponins) nature, as well as amino acids.

AB - This study demonstrated the antioxidant activity of aqueous and aqueous-ethanolic (40%, 70%, 95%) extracts of the above-ground parts of the dropwort (Filipendula vulgaris Moench) in relation to the process of electroreduction of oxygen. Antioxidant properties were more marked in the more lipophilic dropwort extract. The lipophilic fraction of the aqueous extract (extracted with ethyl acetate) had marked antioxidant activity, and its efficacy was greater than those of dihydroquercetin and ascorbic acid, and this resulted from the more complete extraction of total biologically active compounds of phenolic (simple phenols, flavonoids, hydroxycoumarins, phenolcarboxylic acids) and triterpene (acids, saponins) nature, as well as amino acids.

KW - cathodic voltammetry

KW - Filipendula vulgaris Moench

KW - phenolic and triterpene compounds

UR - http://www.scopus.com/inward/record.url?scp=85032680080&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85032680080&partnerID=8YFLogxK

U2 - 10.1007/s11094-017-1660-x

DO - 10.1007/s11094-017-1660-x

M3 - Article

AN - SCOPUS:85032680080

VL - 51

SP - 602

EP - 605

JO - Pharmaceutical Chemistry Journal

JF - Pharmaceutical Chemistry Journal

SN - 0091-150X

IS - 7

ER -