Biologically Active Substances From Dropwort (Filipendula vulgaris) and Assessment of Their Antioxidant Properties

Abstract

This study demonstrated the antioxidant activity of aqueous and aqueous-ethanolic (40%, 70%, 95%) extracts of the above-ground parts of the dropwort (Filipendula vulgaris Moench) in relation to the process of electroreduction of oxygen. Antioxidant properties were more marked in the more lipophilic dropwort extract. The lipophilic fraction of the aqueous extract (extracted with ethyl acetate) had marked antioxidant activity, and its efficacy was greater than those of dihydroquercetin and ascorbic acid, and this resulted from the more complete extraction of total biologically active compounds of phenolic (simple phenols, flavonoids, hydroxycoumarins, phenolcarboxylic acids) and triterpene (acids, saponins) nature, as well as amino acids.

Original language	English
Pages (from-to)	602-605
Number of pages	4
Journal	Pharmaceutical Chemistry Journal
Volume	51
Issue number	7
DOIs	https://doi.org/10.1007/s11094-017-1660-x
Publication status	Published - 1 Oct 2017

Keywords

cathodic voltammetry
Filipendula vulgaris Moench
phenolic and triterpene compounds

ASJC Scopus subject areas

Pharmacology
Drug Discovery

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10.1007/s11094-017-1660-x

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abstract = "This study demonstrated the antioxidant activity of aqueous and aqueous-ethanolic (40%, 70%, 95%) extracts of the above-ground parts of the dropwort (Filipendula vulgaris Moench) in relation to the process of electroreduction of oxygen. Antioxidant properties were more marked in the more lipophilic dropwort extract. The lipophilic fraction of the aqueous extract (extracted with ethyl acetate) had marked antioxidant activity, and its efficacy was greater than those of dihydroquercetin and ascorbic acid, and this resulted from the more complete extraction of total biologically active compounds of phenolic (simple phenols, flavonoids, hydroxycoumarins, phenolcarboxylic acids) and triterpene (acids, saponins) nature, as well as amino acids.",

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author = "Shilova, {I. V.} and Korotkova, {E. I.}",

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N2 - This study demonstrated the antioxidant activity of aqueous and aqueous-ethanolic (40%, 70%, 95%) extracts of the above-ground parts of the dropwort (Filipendula vulgaris Moench) in relation to the process of electroreduction of oxygen. Antioxidant properties were more marked in the more lipophilic dropwort extract. The lipophilic fraction of the aqueous extract (extracted with ethyl acetate) had marked antioxidant activity, and its efficacy was greater than those of dihydroquercetin and ascorbic acid, and this resulted from the more complete extraction of total biologically active compounds of phenolic (simple phenols, flavonoids, hydroxycoumarins, phenolcarboxylic acids) and triterpene (acids, saponins) nature, as well as amino acids.

AB - This study demonstrated the antioxidant activity of aqueous and aqueous-ethanolic (40%, 70%, 95%) extracts of the above-ground parts of the dropwort (Filipendula vulgaris Moench) in relation to the process of electroreduction of oxygen. Antioxidant properties were more marked in the more lipophilic dropwort extract. The lipophilic fraction of the aqueous extract (extracted with ethyl acetate) had marked antioxidant activity, and its efficacy was greater than those of dihydroquercetin and ascorbic acid, and this resulted from the more complete extraction of total biologically active compounds of phenolic (simple phenols, flavonoids, hydroxycoumarins, phenolcarboxylic acids) and triterpene (acids, saponins) nature, as well as amino acids.

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