Biodegradable magnesium coronary stents: Material, design and fabrication

Ali Gökhan Demir, Barbara Previtali, Qiang Ge, Maurizio Vedani, Wei Wu, Francesco Migliavacca, Lorenza Petrini, Carlo Alberto Biffi, Massimiliano Bestetti

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Biodegradable cardiovascular stents in magnesium (Mg) alloys constitute a promising option for a less intrusive treatment, due to their high compatibility with the body tissue and intrinsic dissolution in body fluids. The design and fabrication aspects of this medical device require an integrated approach considering different aspects such as mechanical properties, corrosion behaviour and biocompatibility. This work gathers and summarises a multidisciplinary work carried out by three different research teams for the design and fabrication of Mg stents. In particular, the paper discusses the design of the novel stent mesh, the deformability study of the Mg alloys for tubular raw material and laser microcutting for the realisation of the stent mesh. Although, the results are not fully validated as the device has not been fully tested, they show the feasibility of the used approaches, as the first prototype stents in Mg alloy were produced successfully.

Original languageEnglish
Pages (from-to)936-945
Number of pages10
JournalInternational Journal of Computer Integrated Manufacturing
Volume27
Issue number10
DOIs
Publication statusPublished - 3 Oct 2014
Externally publishedYes

Keywords

  • AZ31
  • biodegradable
  • cardiovascular stent
  • laser microcutting
  • tube extrusion

ASJC Scopus subject areas

  • Aerospace Engineering
  • Mechanical Engineering
  • Computer Science Applications
  • Electrical and Electronic Engineering

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  • Cite this

    Demir, A. G., Previtali, B., Ge, Q., Vedani, M., Wu, W., Migliavacca, F., Petrini, L., Biffi, C. A., & Bestetti, M. (2014). Biodegradable magnesium coronary stents: Material, design and fabrication. International Journal of Computer Integrated Manufacturing, 27(10), 936-945. https://doi.org/10.1080/0951192X.2013.834475