Abstract
Composites based on lactic acid oligomers, calcium hydrophosphate and hydroxyapatite synthesized under the action of microwave radiation were obtained in situ. The appearance of a new band associated with stretching vibrations of >C=O in spectra of the chloroform-insoluble fraction is indicative of the chemical interaction between lactic acid and hydroxyapatite. To determine whether a calcium phosphate layer can be formed on the surface of composite samples, biomimetic studies in a physiological SBF solution were carried out during 28 days at 37 C. It was found that all samples containing calcium phosphates promote active formation of a new calcium phosphate layer, whereas lactic acid oligomer in samples containing no inorganic component undergoes destruction in the SBF solution as a result of hydrolysis. The estimate of the resorption rate demonstrated that the solubility of calcium phosphates contained in the composites at 20 C in the physiological solution is 3-7 times that of pure hydroxyapatite.
Original language | English |
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Pages (from-to) | 669-675 |
Number of pages | 7 |
Journal | Russian Journal of Applied Chemistry |
Volume | 88 |
Issue number | 4 |
DOIs | |
Publication status | Published - 23 Apr 2015 |
ASJC Scopus subject areas
- Chemistry(all)
- Chemical Engineering(all)