Abstract
Sonogashira alkynylation of methyl 2-iodobenzoate with terminal acetylenes gave a series of methyl 2-(alk-1-yn-1-yl)benzoates which reacted with hydroxylamine in boiling methanol to produce five- or six-membered N-hydroxy lactams, 3-R-methylidene-2-hydroxy-2,3-dihydroisoindol-1-ones or 3-R-isoquinolin-1(2H)-ones, depending on the acetylenic substituent nature.
| Original language | English |
|---|---|
| Pages (from-to) | 506-509 |
| Number of pages | 4 |
| Journal | Russian Journal of Organic Chemistry |
| Volume | 50 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 1 Jan 2014 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Organic Chemistry
Cite this
Base-catalyzed heterocyclization of 2-(R-ethynyl)benzohydroxamic acids. / Vasilevskii, S. F.; Mikhailovskaya, T. F.; Stepanov, A. A.; Mamatyuk, V. I.; Fadeev, D. S.
In: Russian Journal of Organic Chemistry, Vol. 50, No. 4, 01.01.2014, p. 506-509.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Base-catalyzed heterocyclization of 2-(R-ethynyl)benzohydroxamic acids
AU - Vasilevskii, S. F.
AU - Mikhailovskaya, T. F.
AU - Stepanov, A. A.
AU - Mamatyuk, V. I.
AU - Fadeev, D. S.
PY - 2014/1/1
Y1 - 2014/1/1
N2 - Sonogashira alkynylation of methyl 2-iodobenzoate with terminal acetylenes gave a series of methyl 2-(alk-1-yn-1-yl)benzoates which reacted with hydroxylamine in boiling methanol to produce five- or six-membered N-hydroxy lactams, 3-R-methylidene-2-hydroxy-2,3-dihydroisoindol-1-ones or 3-R-isoquinolin-1(2H)-ones, depending on the acetylenic substituent nature.
AB - Sonogashira alkynylation of methyl 2-iodobenzoate with terminal acetylenes gave a series of methyl 2-(alk-1-yn-1-yl)benzoates which reacted with hydroxylamine in boiling methanol to produce five- or six-membered N-hydroxy lactams, 3-R-methylidene-2-hydroxy-2,3-dihydroisoindol-1-ones or 3-R-isoquinolin-1(2H)-ones, depending on the acetylenic substituent nature.
UR - http://www.scopus.com/inward/record.url?scp=84901450387&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84901450387&partnerID=8YFLogxK
U2 - 10.1134/S1070428014040101
DO - 10.1134/S1070428014040101
M3 - Article
VL - 50
SP - 506
EP - 509
JO - Russian Journal of Organic Chemistry
JF - Russian Journal of Organic Chemistry
SN - 1070-4280
IS - 4
ER -