Barstar: barnase - A versatile platform for colloidal diamond bioconjugation

Varun K A Sreenivasan, Ekaterina A. Ivukina, Wei Deng, Timothy A. Kelf, Tatyana A. Zdobnova, Sergey V. Lukash, Boris V. Veryugin, Oleg A. Stremovskiy, Andrei V. Zvyagin, Sergey M. Deyev

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29 Citations (Scopus)

Abstract

We report on a bioconjugation platform based on a high-affinity protein pair, barstar:barnase (Bs:Bn), that provides a modular design toolkit capable of strong (covalent) and versatile assembly of bio/nanocomplexes. Luminescent nanodiamonds (140 nm) serve as the docking station to synthesize Bs:Bn bioconjugates which are characterized and utilized in several applications, including cell transfection.

Original languageEnglish
Pages (from-to)65-68
Number of pages4
JournalJournal of Materials Chemistry
Volume21
Issue number1
DOIs
Publication statusPublished - 7 Jan 2011
Externally publishedYes

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ASJC Scopus subject areas

  • Chemistry(all)
  • Materials Chemistry

Cite this

Sreenivasan, V. K. A., Ivukina, E. A., Deng, W., Kelf, T. A., Zdobnova, T. A., Lukash, S. V., ... Deyev, S. M. (2011). Barstar: barnase - A versatile platform for colloidal diamond bioconjugation. Journal of Materials Chemistry, 21(1), 65-68. https://doi.org/10.1039/c0jm02819c