Abstract
A simple, convenient, and environment-friendly procedure for the preparation of substituted biaryls via Suzuki-Miyaura cross-coupling was developed. The use of arenediazonium tosylates and corresponding boron compounds allows a conversion in neat water in the presence of commercially available Pd(OAc)2 under mild conditions with tolerance to a wide range of functional groups. A procedure particularly useful for the synthesis of di-ortho-substituted biaryls was developed.
| Original language | English |
|---|---|
| Article number | ss-2016-z0633-op |
| Pages (from-to) | 1680-1688 |
| Number of pages | 9 |
| Journal | Synthesis (Germany) |
| Volume | 49 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - 1 Apr 2017 |
Keywords
- arenediazonium salts
- arenediazonium tosylates
- biphenyls
- Suzuki-Miyaura reactions
- water media
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry
Fingerprint Dive into the research topics of 'Arenediazonium Tosylates (ADTs) as Efficient Reagents for Suzuki-Miyaura Cross-Coupling in Neat Water'. Together they form a unique fingerprint.
Cite this
Kutonova, K. V., Jung, N., Trusova, M. E., Filimonov, V. D., Postnikov, P. S., & Bräse, S. (2017). Arenediazonium Tosylates (ADTs) as Efficient Reagents for Suzuki-Miyaura Cross-Coupling in Neat Water. Synthesis (Germany), 49(7), 1680-1688. [ss-2016-z0633-op]. https://doi.org/10.1055/s-0036-1588919