Abstract
Sulfur-containing biologically active substances (BAS) demonstrate pronounced antioxidant properties. Glutathione, cysteine, cystine, methionine, taurine, and lipoic acid occupy special positions among sulfur-containing antioxidant compounds. The antioxidant properties of these sulfur-containing BAS have been characterized and analyzed using voltammetric and spectrophotometric data. All studied BAS showed more or less pronounced antioxidant activity. Lipoic acid and glutathione exhibited the maximum antioxidant activity, which agrees with data published in the literature. Methionine showed the minimum antioxidant activity among the group of investigated BAS. The antioxidant activity was compared on the basis of the international criterion of antioxidant properties of sulfur-containing BAS, oxygen radical absorbance capacity (ORAC) with respect to a reference antioxidant (glutathione). A correlation was found between results of the voltammetric and spectrophotometric analyses.
| Original language | English |
|---|---|
| Pages (from-to) | 581-584 |
| Number of pages | 4 |
| Journal | Pharmaceutical Chemistry Journal |
| Volume | 44 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - Jan 2011 |
Fingerprint
Keywords
- antioxidant activity
- spectrophotometry
- sulfur-containing biologically active substances
- voltammetry
ASJC Scopus subject areas
- Drug Discovery
- Pharmacology
Cite this
Antioxidant properties of sulfur-containing biologically active substances studied by voltammetric and spectrophotometric techniques. / Dorozhko, E. V.; Korotkova, E. I.
In: Pharmaceutical Chemistry Journal, Vol. 44, No. 10, 01.2011, p. 581-584.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Antioxidant properties of sulfur-containing biologically active substances studied by voltammetric and spectrophotometric techniques
AU - Dorozhko, E. V.
AU - Korotkova, E. I.
PY - 2011/1
Y1 - 2011/1
N2 - Sulfur-containing biologically active substances (BAS) demonstrate pronounced antioxidant properties. Glutathione, cysteine, cystine, methionine, taurine, and lipoic acid occupy special positions among sulfur-containing antioxidant compounds. The antioxidant properties of these sulfur-containing BAS have been characterized and analyzed using voltammetric and spectrophotometric data. All studied BAS showed more or less pronounced antioxidant activity. Lipoic acid and glutathione exhibited the maximum antioxidant activity, which agrees with data published in the literature. Methionine showed the minimum antioxidant activity among the group of investigated BAS. The antioxidant activity was compared on the basis of the international criterion of antioxidant properties of sulfur-containing BAS, oxygen radical absorbance capacity (ORAC) with respect to a reference antioxidant (glutathione). A correlation was found between results of the voltammetric and spectrophotometric analyses.
AB - Sulfur-containing biologically active substances (BAS) demonstrate pronounced antioxidant properties. Glutathione, cysteine, cystine, methionine, taurine, and lipoic acid occupy special positions among sulfur-containing antioxidant compounds. The antioxidant properties of these sulfur-containing BAS have been characterized and analyzed using voltammetric and spectrophotometric data. All studied BAS showed more or less pronounced antioxidant activity. Lipoic acid and glutathione exhibited the maximum antioxidant activity, which agrees with data published in the literature. Methionine showed the minimum antioxidant activity among the group of investigated BAS. The antioxidant activity was compared on the basis of the international criterion of antioxidant properties of sulfur-containing BAS, oxygen radical absorbance capacity (ORAC) with respect to a reference antioxidant (glutathione). A correlation was found between results of the voltammetric and spectrophotometric analyses.
KW - antioxidant activity
KW - spectrophotometry
KW - sulfur-containing biologically active substances
KW - voltammetry
UR - http://www.scopus.com/inward/record.url?scp=79953204558&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=79953204558&partnerID=8YFLogxK
U2 - 10.1007/s11094-011-0521-2
DO - 10.1007/s11094-011-0521-2
M3 - Article
VL - 44
SP - 581
EP - 584
JO - Pharmaceutical Chemistry Journal
JF - Pharmaceutical Chemistry Journal
SN - 0091-150X
IS - 10
ER -