Antihypoxic activity of native humic acids of Tomsk lowland peat

M. V. Belousov, R. R. Akhmedzhanov, M. V. Zykova, A. N. Arbuzov, A. M. Gur'ev, M. S. Yusubov

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The antihypoxic activity of humic acids of Tomsk lowland peat was studied experimentally. It was established that native humic acids of peat (HAP) had pronounced antihypoxic activity after a preventive intragastric administration to mice, increasing the lifespan of animals and decreasing the lethality under hypobaric hypoxic and histotoxic hypoxia conditions. The discovered antihypoxic properties of HAP were probably due to their protective antioxidant properties, which prevent free-radical injury to cells and organelles under hypoxia conditions.

Original languageEnglish
Pages (from-to)97-99
Number of pages3
JournalPharmaceutical Chemistry Journal
Volume48
Issue number2
DOIs
Publication statusPublished - 2014

Fingerprint

Humic Substances
Soil
Organelles
Free Radicals
Antioxidants
Wounds and Injuries
Hypoxia

Keywords

  • Antihypoxic activity
  • Humic acids
  • Peat

ASJC Scopus subject areas

  • Drug Discovery
  • Pharmacology

Cite this

Antihypoxic activity of native humic acids of Tomsk lowland peat. / Belousov, M. V.; Akhmedzhanov, R. R.; Zykova, M. V.; Arbuzov, A. N.; Gur'ev, A. M.; Yusubov, M. S.

In: Pharmaceutical Chemistry Journal, Vol. 48, No. 2, 2014, p. 97-99.

Research output: Contribution to journalArticle

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