Antibacterial AgNPs/CaP biocomposites

A. A. Ivanova, R. A. Surmenev, M. A. Surmeneva, Timur Mukhamedrashidovich Mukhametkaliyev, A. A. Sharonova, I. Yu Grubova, K. Loza, S. Chernousova, O. Prymak, M. Epple

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

The modification of implant surface is in the focus of many scientists worldwide. In this study, multifunctional biocomposite on the basis of calcium phosphate coating and silver nanoparticles has been fabricated through the use of nanofabrication techniques. Dense nanocrystalline HA film was deposited over AgNPs. The properties as well as the in vitro behavior of the developed biocomposites have been studied. The diffraction patterns of the biocomposites revealed the peaks of crystalline HA and silver (Ag). The release of Ag from the developed biocomposites was evaluated. The concentration of the released silver ions for 7 days of dissolution was 0.27±0.02 μg/mL and 0.54±0.02 μg/mL for phosphate and acetate buffers, respectively. In order to estimate the cytotoxicity of the samples the functional activity of osteoclasts, in particular, cell morphology, multinuclearity, actin ring and resorption pit on the substrates coated with HA and AgNPs-HA have been evaluated.

Original languageEnglish
Title of host publication2014 9th International Forum on Strategic Technology, IFOST 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages472-474
Number of pages3
ISBN (Print)9781479960620
DOIs
Publication statusPublished - 17 Dec 2014
Event9th International Forum on Strategic Technology, IFOST 2014 - Cox's Bazar, Bangladesh
Duration: 21 Oct 201423 Oct 2014

Other

Other9th International Forum on Strategic Technology, IFOST 2014
CountryBangladesh
CityCox's Bazar
Period21.10.1423.10.14

Keywords

  • hydroxyapatite
  • multilayer structures
  • RF magnetron sputtering
  • silver nanoparticles
  • thin films

ASJC Scopus subject areas

  • Energy Engineering and Power Technology
  • Civil and Structural Engineering
  • Building and Construction
  • Fuel Technology
  • Computer Networks and Communications

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  • Cite this

    Ivanova, A. A., Surmenev, R. A., Surmeneva, M. A., Mukhametkaliyev, TM., Sharonova, A. A., Grubova, I. Y., Loza, K., Chernousova, S., Prymak, O., & Epple, M. (2014). Antibacterial AgNPs/CaP biocomposites. In 2014 9th International Forum on Strategic Technology, IFOST 2014 (pp. 472-474). [6991166] Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/IFOST.2014.6991166