An improved procedure for the preparation of aryl- and hetarylacetylenes

A. G. Mal'Kina, L. Brandsma, S. F. Vasilevsky, B. A. Trofimov

Research output: Contribution to journalArticlepeer-review

37 Citations (Scopus)


A number of relatively volatile acetylenes RC ≡ CH (R = aryl or hetaryl) have been prepared with high yields by heating a mixture of the corresponding alcohols RC ≡ CC(CH3)2OH and paraffin oil with small amounts of powdered potassium hydroxide in vacuum. The alcohols were obtained by Pd/Cu-catalyzed cross coupling of aryl or hetaryl halides RX (X = Br, in one case I) with the commercially available HC ≡ CC(CH3)2OH.

Original languageEnglish
Pages (from-to)589-590
Number of pages2
Issue number5
Publication statusPublished - 1 Jan 1996
Externally publishedYes


  • acetylenic alcohols
  • hetarylacetylenes
  • KOH-catalyzed elimination of acetone
  • retro-Favorsky reaction
  • synthesis of 2-iodo-1-methylpyrrole

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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