An expeditious and environmentally benign preparation of aryl halides from aryl amines by solvent-free grinding

Mi Eun Moon, Younghwa Choi, Young Min Lee, Vaishali Vajpayee, Marina Trusova, Victor D. Filimonov, Ki Whan Chi

Research output: Contribution to journal › Article

23 Citations (Scopus)

Abstract

An efficient solvent-free methodology for conversion of various aryl amines into bromides and chlorides via arenediazonium tosylate salts under grinding conditions is disclosed. This new methodology not only avoids the use of strong acids and expensive reagents for diazotization-halogenation reactions, but also decreases the amount of organic waste from the reaction process.

Original languageEnglish
Pages (from-to)6769-6771
Number of pages3
JournalTetrahedron Letters
Volume51
Issue number51
DOIs
Publication statusPublished - 22 Dec 2010

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Halogenation
Bromides
Amines
Chlorides
Salts
Acids

Keywords

  • Arenediazonium tosylate salt
  • Halogenation
  • Solvent-free grinding

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

An expeditious and environmentally benign preparation of aryl halides from aryl amines by solvent-free grinding. / Moon, Mi Eun; Choi, Younghwa; Lee, Young Min; Vajpayee, Vaishali; Trusova, Marina; Filimonov, Victor D.; Chi, Ki Whan.

In: Tetrahedron Letters, Vol. 51, No. 51, 22.12.2010, p. 6769-6771.

Research output: Contribution to journal › Article

Moon, ME, Choi, Y, Lee, YM, Vajpayee, V, Trusova, M, Filimonov, VD & Chi, KW 2010, 'An expeditious and environmentally benign preparation of aryl halides from aryl amines by solvent-free grinding', Tetrahedron Letters, vol. 51, no. 51, pp. 6769-6771. https://doi.org/10.1016/j.tetlet.2010.10.099
Moon ME, Choi Y, Lee YM, Vajpayee V, Trusova M, Filimonov VD et al. An expeditious and environmentally benign preparation of aryl halides from aryl amines by solvent-free grinding. Tetrahedron Letters. 2010 Dec 22;51(51):6769-6771. https://doi.org/10.1016/j.tetlet.2010.10.099
Moon, Mi Eun ; Choi, Younghwa ; Lee, Young Min ; Vajpayee, Vaishali ; Trusova, Marina ; Filimonov, Victor D. ; Chi, Ki Whan. / An expeditious and environmentally benign preparation of aryl halides from aryl amines by solvent-free grinding. In: Tetrahedron Letters. 2010 ; Vol. 51, No. 51. pp. 6769-6771.
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AU - Filimonov, Victor D.

AU - Chi, Ki Whan

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