Abstract
The pKa values of 1-indolylacetic, 3-(9-ethyl)carbazolylacetic, and a number of 3,6-disubstituted 9-carbazolylacetic acids in aqueous ethanol solutions were determined by potentiometry.The inductive constants of the corresponding heterocyclic fragments were calculated from the values obtained. It is shown that annelation of the benzene ring with the pyrrole ring of indole gives rise to a decrease in the negative inductive effect of the heteroring. A linear relationship between the acidic properties of carbazoles and the corresponding 9-carbazolylacetic acids was established.
| Original language | English |
|---|---|
| Pages (from-to) | 1213-1216 |
| Number of pages | 4 |
| Journal | Chemistry of Heterocyclic Compounds |
| Volume | 17 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - Dec 1981 |
ASJC Scopus subject areas
- Organic Chemistry
Fingerprint Dive into the research topics of 'Acidities of 1-indolylacetic and carbazolylacetic acids. Inductive constants of indolyl and carbazolyl groups'. Together they form a unique fingerprint.
Cite this
Filimonov, V. D., Sukhoroslova, M. M., Novikov, V. T., & Vidyagina, T. V. (1981). Acidities of 1-indolylacetic and carbazolylacetic acids. Inductive constants of indolyl and carbazolyl groups. Chemistry of Heterocyclic Compounds, 17(12), 1213-1216. https://doi.org/10.1007/BF00506996