Acetylene derivatives of heterocycles - III. Synthesis of N-alkylpyrazolylacetylenes from methyl pyrazolyl ketones

M. S. Shvartsberg, S. F. Vasilevskii, V. G. Kostrovskii, I. L. Kotlyarevskii

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3 Citations (Scopus)

Abstract

4-Ethynyl-1,3,5-trimethylpyrazole and 3,5-diethynyl-1-methylpyrazole have been synthesized by the reaction of the corresponding methyl N-methyl-pyrazolyl ketones with PCl5 followed by dehydrochlorination. 4-Butadiynyl-1,3,5-trimethylpyrazole has been obtained similarly from 4-acetoacetyl-1,3,5-trimethylpyrazole. The N-substituted pyrazolylacetylenes have been subjected to the Chodkiewicz-Cadiot reaction and to dehydrocondensation. The IR spectra of the acetylene derivatives of pyrazole synthesized are discussed.

Original languageEnglish
Pages (from-to)797-800
Number of pages4
JournalChemistry of Heterocyclic Compounds
Volume5
Issue number6
DOIs
Publication statusPublished - 1 Nov 1972
Externally publishedYes

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Acetylene
Ketones
Derivatives
pyrazole

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Acetylene derivatives of heterocycles - III. Synthesis of N-alkylpyrazolylacetylenes from methyl pyrazolyl ketones. / Shvartsberg, M. S.; Vasilevskii, S. F.; Kostrovskii, V. G.; Kotlyarevskii, I. L.

In: Chemistry of Heterocyclic Compounds, Vol. 5, No. 6, 01.11.1972, p. 797-800.

Research output: Contribution to journalArticle

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AU - Kostrovskii, V. G.

AU - Kotlyarevskii, I. L.

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