TY - JOUR
T1 - A stepwise huisgen cycloaddition process
T2 - Copper(I)-catalyzed regioselective "ligation" of azides and terminal alkynes
AU - Rostovtsev, Vsevolod V.
AU - Green, Luke G.
AU - Fokin, Valery V.
AU - Sharpless, K. Barry
PY - 2002/7/15
Y1 - 2002/7/15
N2 - By simply stirring in water, organic azides and terminal alkynes are readily and cleanly converted into 1,4-disubstituted 1,2,3-triazoles through a highly efficient and regioselective copper(I)-catalyzed process (see scheme for an example).
AB - By simply stirring in water, organic azides and terminal alkynes are readily and cleanly converted into 1,4-disubstituted 1,2,3-triazoles through a highly efficient and regioselective copper(I)-catalyzed process (see scheme for an example).
KW - Azides
KW - Copper
KW - Cycloaddition
KW - Homogeneous catalysis
KW - Nitrogen heterocycles
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U2 - 10.1002/1521-3773(20020715)41:14<2596::AID-ANIE2596>3.0.CO;2-4
DO - 10.1002/1521-3773(20020715)41:14<2596::AID-ANIE2596>3.0.CO;2-4
M3 - Article
C2 - 12203546
AN - SCOPUS:0037099395
VL - 41
SP - 2596
EP - 2599
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
SN - 1433-7851
IS - 14
ER -