Doklinicheskaia otsenka bezopasnosti iodantipirina.

Translated title of the contribution: A preclinical trial of iodoantipyrine safety

A. S. Saratikov, T. P. Novozheeva, N. S. Livshits, F. I. Burchenkova, N. G. Kadychagova, R. R. Akhmedzhanov, L. V. Bashirova, A. A. Eremina, G. V. Potapova

Division for Control and Diagnostics

Research output: Contribution to journal › Article › peer-review

Abstract

Detailed preclinical study of the safety of the new antiviral agent iodantipyrine was conducted. In LD50 parameters it was found to be related to moderately toxic drugs. Long-term administration in doses of 50, 100, and 250 mg/kg did not cause any essential functional and structural disorders in the organs and systems of rats and dogs. Iodantipyrine does not possess mutagenic and allergenic properties and does not affect the reproductive function.

Translated title of the contribution	A preclinical trial of iodoantipyrine safety
Original language	Russian
Pages (from-to)	57-59
Number of pages	3
Journal	Eksperimental'naia i klinicheskaia farmakologiia
Volume	61
Issue number	2
Publication status	Published - Mar 1998

ASJC Scopus subject areas

Pharmacology, Toxicology and Pharmaceutics(all)

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Doklinicheskaia otsenka bezopasnosti iodantipirina. / Saratikov, A. S.; Novozheeva, T. P.; Livshits, N. S.; Burchenkova, F. I.; Kadychagova, N. G.; Akhmedzhanov, R. R.; Bashirova, L. V.; Eremina, A. A.; Potapova, G. V.

In: Eksperimental'naia i klinicheskaia farmakologiia, Vol. 61, No. 2, 03.1998, p. 57-59.

Research output: Contribution to journal › Article › peer-review

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title = "Doklinicheskaia otsenka bezopasnosti iodantipirina.",

abstract = "Detailed preclinical study of the safety of the new antiviral agent iodantipyrine was conducted. In LD50 parameters it was found to be related to moderately toxic drugs. Long-term administration in doses of 50, 100, and 250 mg/kg did not cause any essential functional and structural disorders in the organs and systems of rats and dogs. Iodantipyrine does not possess mutagenic and allergenic properties and does not affect the reproductive function.",

author = "Saratikov, {A. S.} and Novozheeva, {T. P.} and Livshits, {N. S.} and Burchenkova, {F. I.} and Kadychagova, {N. G.} and Akhmedzhanov, {R. R.} and Bashirova, {L. V.} and Eremina, {A. A.} and Potapova, {G. V.}",

year = "1998",

month = mar,

language = "Русский",

volume = "61",

pages = "57--59",

journal = "Eksperimental'naya i Klinicheskaya Farmakologiya",

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AU - Saratikov, A. S.

AU - Novozheeva, T. P.

AU - Livshits, N. S.

AU - Burchenkova, F. I.

AU - Kadychagova, N. G.

AU - Akhmedzhanov, R. R.

AU - Bashirova, L. V.

AU - Eremina, A. A.

AU - Potapova, G. V.

PY - 1998/3

Y1 - 1998/3

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AB - Detailed preclinical study of the safety of the new antiviral agent iodantipyrine was conducted. In LD50 parameters it was found to be related to moderately toxic drugs. Long-term administration in doses of 50, 100, and 250 mg/kg did not cause any essential functional and structural disorders in the organs and systems of rats and dogs. Iodantipyrine does not possess mutagenic and allergenic properties and does not affect the reproductive function.

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SN - 0869-2092

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