The first method for the direct one-pot transformation of aminopyridines into pyridinyl trifluoromethanesulfonates is developed. The procedure involves diazotization of aminopyridines with sodium nitrite in a DMSO paste in the presence of trifluoromethanesulfonic acid.
- Trifluoromethanesulfonic acid
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry