Abstract
A new single-stage synthesis of betulin phenylcarbamates is suggested that uses 1-phenylurea as a reagent for betulin O-carbamoylation. A chemoselectivity of hydroxyl-groups in carbamoylation of betulin with 1-phenylurea appeared to occur. Synthesized nitrogen-containing betulin derivatives–phenylcarbamates are valuable as bioactive substances.
| Original language | English |
|---|---|
| Pages (from-to) | 1162-1166 |
| Number of pages | 5 |
| Journal | Journal of Asian Natural Products Research |
| Volume | 20 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - 2 Dec 2018 |
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Keywords
- 1-phenylurea
- betulin
- O-carbamoylation
- Pentacyclic triterpenoids
- phenylcarbamates
- phenylisocyanate
ASJC Scopus subject areas
- Analytical Chemistry
- Molecular Medicine
- Pharmacology
- Pharmaceutical Science
- Drug Discovery
- Complementary and alternative medicine
- Organic Chemistry
Cite this
A new single-stage method for obtaining of betulin phenylcarbamates. / Mamaeva, A. Elena; Kaliyeva, S. Saltanat; Bakibaev, A. Abdigali; Tashenov, K. Auezkhan; Nurpeiis, E. Yenglik.
In: Journal of Asian Natural Products Research, Vol. 20, No. 12, 02.12.2018, p. 1162-1166.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - A new single-stage method for obtaining of betulin phenylcarbamates
AU - Mamaeva, A. Elena
AU - Kaliyeva, S. Saltanat
AU - Bakibaev, A. Abdigali
AU - Tashenov, K. Auezkhan
AU - Nurpeiis, E. Yenglik
PY - 2018/12/2
Y1 - 2018/12/2
N2 - A new single-stage synthesis of betulin phenylcarbamates is suggested that uses 1-phenylurea as a reagent for betulin O-carbamoylation. A chemoselectivity of hydroxyl-groups in carbamoylation of betulin with 1-phenylurea appeared to occur. Synthesized nitrogen-containing betulin derivatives–phenylcarbamates are valuable as bioactive substances.
AB - A new single-stage synthesis of betulin phenylcarbamates is suggested that uses 1-phenylurea as a reagent for betulin O-carbamoylation. A chemoselectivity of hydroxyl-groups in carbamoylation of betulin with 1-phenylurea appeared to occur. Synthesized nitrogen-containing betulin derivatives–phenylcarbamates are valuable as bioactive substances.
KW - 1-phenylurea
KW - betulin
KW - O-carbamoylation
KW - Pentacyclic triterpenoids
KW - phenylcarbamates
KW - phenylisocyanate
UR - http://www.scopus.com/inward/record.url?scp=85030682883&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85030682883&partnerID=8YFLogxK
U2 - 10.1080/10286020.2017.1382480
DO - 10.1080/10286020.2017.1382480
M3 - Article
VL - 20
SP - 1162
EP - 1166
JO - Journal of Asian Natural Products Research
JF - Journal of Asian Natural Products Research
SN - 1028-6020
IS - 12
ER -