Abstract
The diazotization of a series of N -oxides of aminopyridines and aminoquinolines under the action of sodium nitrite in the presence of KI and p -TsOH in water at room temperature leads to the formation of the corresponding N -oxides of iodopyridines and iodoquinolines in high yields. The method has a general character and can be used for the preparation of 3-, 2-, and 4- N -oxides of iodopyridines.
Original language | English |
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Pages (from-to) | 1368-1372 |
Number of pages | 5 |
Journal | Synthesis (Germany) |
Volume | 50 |
Issue number | 6 |
DOIs | |
Publication status | Accepted/In press - 13 Dec 2017 |
Keywords
- diazo compounds
- halogenation
- iodine
- pyridines
- quinolines
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry