A new approach to osmium-catalyzed asymmetric dihydroxylation and aminohydroxylation of olefins

Malin A. Andersson, Robert Epple, Valery V. Fokin, K. Barry Sharpless

Research output: Contribution to journalArticle

83 Citations (Scopus)

Abstract

Simple hydroxyamino acid derivatives act as chiral ligands in osmium-catalyzed dihydroxylation and aminohydroxylation of olefins (see scheme). These are the first examples of asymmetric osmium-catalyzed processes proceeding in the second catalytic cycle with resident ligands on the metal center.

Original languageEnglish
Pages (from-to)472-475
Number of pages4
JournalAngewandte Chemie - International Edition
Volume41
Issue number3
DOIs
Publication statusPublished - 1 Feb 2002
Externally publishedYes

Fingerprint

Osmium
Alkenes
Olefins
Ligands
Metals
Derivatives
Acids

Keywords

  • Alkenes
  • Aminohydroxylation
  • Dihydroxylation
  • Homogeneous catalysis
  • Osmium

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

A new approach to osmium-catalyzed asymmetric dihydroxylation and aminohydroxylation of olefins. / Andersson, Malin A.; Epple, Robert; Fokin, Valery V.; Sharpless, K. Barry.

In: Angewandte Chemie - International Edition, Vol. 41, No. 3, 01.02.2002, p. 472-475.

Research output: Contribution to journalArticle

Andersson, Malin A. ; Epple, Robert ; Fokin, Valery V. ; Sharpless, K. Barry. / A new approach to osmium-catalyzed asymmetric dihydroxylation and aminohydroxylation of olefins. In: Angewandte Chemie - International Edition. 2002 ; Vol. 41, No. 3. pp. 472-475.
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