Methods suitable for the decontamination and destruction of selected anti-cancer drugs with possible genotoxic effects on hospital statt coming into contact with those drugs during their preparation, application or during contact with contaminated hospital wastes have been reviewed. These methods, developed in co-operation with our laboratories and verified by International Agency for Research on Cancer, are applicable to the following anti-cancer drugs: amsacrine, azathioprine, carmustine, chlorozotocine, cis-platin, cyclofosfamide, daunorubicin, dichlormethotrexat, doxorubicin, ifosfamid, lomustine, melphalan, 6-merkaptopurine, methotrcxat, semustine, streptozotocine, 6-thioguanine, thiotepa, vincristine, and vinblastine. For their application on structurally similar anti-cancer drugs, it is necessary to first verify their chemical and biological effectiveness.
|Translated title of the contribution||A contribution to laboratory methods of destruction of anti-tumour pharmaceuticals|
|Number of pages||4|
|Publication status||Published - 25 May 2008|
- Anti-tumour drugs
ASJC Scopus subject areas