1,3-Bis(1,2,4-triazol-1-yl)adamantane

Roman Marchenko, Andrei Potapov

Research output: Contribution to journalComment/debate

2 Citations (Scopus)

Abstract

Functional adamantane derivatives are interesting as active pharmaceutical ingredients, building blocks for supramolecular ensembles, and ligands in light of the coordination chemistry of functional materials. In this communication, synthesis of two isomeric 1,3-bis(1,2,4- triazolyl)adamantanes by the reaction of 1,3-dibromoadamantane with 1,2,4-triazole in the absence of solvent is reported. The products, namely 1,3-bis(1,2,4-triazol-1-yl)adamantane and 1-(1,2,4-triazol- 1-yl)-3-(1,2,4-triazol-4-yl)adamantane were separated by column chromatography and identified by NMR and mass-spectrometry.

Original languageEnglish
Article numberM968
JournalMolBank
Volume2017
Issue number4
DOIs
Publication statusPublished - 12 Dec 2017

Keywords

  • 1,2,4-triazole
  • Adamantane
  • Adamantylation
  • Alkylation
  • Bitopic ligand
  • Substitution reaction

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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