1,3-Bis(1,2,4-triazol-1-yl)adamantane

Roman Marchenko, Andrei Potapov

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

Abstract

Functional adamantane derivatives are interesting as active pharmaceutical ingredients, building blocks for supramolecular ensembles, and ligands in light of the coordination chemistry of functional materials. In this communication, synthesis of two isomeric 1,3-bis(1,2,4- triazolyl)adamantanes by the reaction of 1,3-dibromoadamantane with 1,2,4-triazole in the absence of solvent is reported. The products, namely 1,3-bis(1,2,4-triazol-1-yl)adamantane and 1-(1,2,4-triazol- 1-yl)-3-(1,2,4-triazol-4-yl)adamantane were separated by column chromatography and identified by NMR and mass-spectrometry.

Original languageEnglish
Article numberM968
JournalMolBank
Volume2017
Issue number4
DOIs
Publication statusPublished - 12 Dec 2017

Fingerprint

Adamantane
chromatography
ingredients
mass spectroscopy
communication
chemistry
nuclear magnetic resonance
ligands
synthesis
products
Column chromatography
Functional materials
Mass spectrometry
Chromatography
Mass Spectrometry
Nuclear magnetic resonance
Ligands
Derivatives
Communication
Pharmaceutical Preparations

Keywords

  • 1,2,4-triazole
  • Adamantane
  • Adamantylation
  • Alkylation
  • Bitopic ligand
  • Substitution reaction

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

1,3-Bis(1,2,4-triazol-1-yl)adamantane. / Marchenko, Roman; Potapov, Andrei.

In: MolBank, Vol. 2017, No. 4, M968, 12.12.2017.

Research output: Contribution to journalComment/debate

Marchenko, Roman ; Potapov, Andrei. / 1,3-Bis(1,2,4-triazol-1-yl)adamantane. In: MolBank. 2017 ; Vol. 2017, No. 4.
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