• 1952 Citations
  • 22 h-Index
1992 …2020

Research output per year

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Research Output

  • 1952 Citations
  • 22 h-Index
  • 56 Article
  • 3 Review article
2020

Inhibitory effect of IQ-1S, a selective c-Jun N-terminal kinase (JNK) inhibitor, on phenotypical and cytokine-producing characteristics in human macrophages and T-cells

Seledtsov, V. I., Malashchenko, V. V., Meniailo, M. E., Atochin, D. N., Seledtsova, G. V. & Schepetkin, I. A., 5 Jul 2020, In : European Journal of Pharmacology. 878, 173116.

Research output: Contribution to journalArticle

2019

cGMP-dependent protein kinase I in vascular smooth muscle cells improves ischemic stroke outcome in mice

Shvedova, M., Litvak, M. M., Roberts, J. D., Fukumura, D., Suzuki, T., Şencan, İ., Li, G., Reventun, P., Buys, E. S., Kim, H. H., Sakadžić, S., Ayata, C., Huang, P. L., Feil, R. & Atochin, D. N., 1 Dec 2019, In : Journal of Cerebral Blood Flow and Metabolism. 39, 12, p. 2379-2391 13 p.

Research output: Contribution to journalArticle

Open Access

Protective Effects of a New C-Jun N-terminal Kinase Inhibitor in the Model of Global Cerebral Ischemia in Rats

Plotnikov, M. B., Chernysheva, G. A., Aliev, O. I., Smol'iakova, V. I., Fomina, T. I., Osipenko, A. N., Rydchenko, V. S., Anfinogenova, Y. J., Khlebnikov, A. I., Schepetkin, I. A. & Atochin, D. N., 1 Jan 2019, In : Molecules. 24, 9, 1722.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Synthesis, biological evaluation, and molecular modeling of 11H-indeno[1,2-b]quinoxalin-11-one derivatives and tryptanthrin-6-oxime as c-Jun N-terminal kinase inhibitors

Schepetkin, I. A., Khlebnikov, A. I., Potapov, A. S., Kovrizhina, A. R., Matveevskaya, V. V., Belyanin, M. L., Atochin, D. N., Zanoza, S. O., Gaidarzhy, N. M., Lyakhov, S. A., Kirpotina, L. N. & Quinn, M. T., 1 Jan 2019, In : European Journal of Medicinal Chemistry. 161, p. 179-191 13 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2018

c-Jun N-terminal kinases (JNKs) in myocardial and cerebral ischemia/reperfusion injury

Shvedova, M., Anfinogenova, Y., Atochina-Vasserman, E. N., Schepetkin, I. A. & Atochin, D. N., 5 Jul 2018, In : Frontiers in Pharmacology. 9, JUL, 715.

Research output: Contribution to journalReview article

22 Citations (Scopus)
1 Citation (Scopus)

Haplotype analysis of endothelial nitric oxide synthase (NOS3) genetic variants and metabolic syndrome in healthy subjects and schizophrenia patients

Fattakhov, N., Smirnova, L., Atochin, D., Parshukova, D., Skuratovskaia, D., Painter, Q., Zatolokin, P., Semke, A., Litvinova, L. & Ivanova, S., 15 Jun 2018, (Accepted/In press) In : International Journal of Obesity. p. 1-11 11 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Quantitative assessment of demyelination in ischemic stroke in vivo using macromolecular proton fraction mapping

Khodanovich, M. Y., Kisel, A. A., Akulov, A. E., Atochin, D. N., Kudabaeva, M. S., Glazacheva, V. Y., Svetlik, M. V., Medvednikova, Y. A., Mustafina, L. R. & Yarnykh, V. L., 1 Jan 2018, (Accepted/In press) In : Journal of Cerebral Blood Flow and Metabolism. 38, 5, p. 919-931 13 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2017

An improved three-vessel occlusion model of global cerebral ischemia in rats

Atochin, D. N., Chernysheva, G. A., Aliev, O. I., Smolyakova, V. I., Osipenko, A. N., Logvinov, S. V., Zhdankina, A. A., Plotnikova, T. M. & Plotnikov, M. B., 1 Jun 2017, In : Brain Research Bulletin. 132, p. 213-221 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Cell-Based Drug Delivery and Use of Nano-and Microcarriers for Cell Functionalization

Timin, A. S., Litvak, M. M., Gorin, D. A., Atochina-Vasserman, E. N., Atochin, D. N. & Sukhorukov, G. B., 1 Jan 2017, (Accepted/In press) In : Advanced healthcare materials. 7, 3, 1700818.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Role of eNOS in water exchange index maintenance-MRI studies

Atochin, D., Litvak, M., Huang, S., Kim, Y. R. & Huang, P., 29 Aug 2017, In : Journal of Physics: Conference Series. 886, 1, 012002.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Targeting thrombomodulin to circulating red blood cells augments its protective effects in models of endotoxemia and ischemia-reperfusion injury

Carnemolla, R., Villa, C. H., Greineder, C. F., Zaitsev, S., Patel, K. R., Kowalska, M. A., Atochin, D. N., Cines, D. B., Siegel, D. L., Esmon, C. T. & Muzykantov, V. R., 1 Feb 2017, In : FASEB Journal. 31, 2, p. 761-770 10 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
2016

A novel dual NO-donating oxime and c-Jun N-terminal kinase inhibitor protects against cerebral ischemia-reperfusion injury in mice

Atochin, D. N., Shchepetkin, I. A., Khlebnikov, A. I., Seledtsov, V. I., Swanson, H., Quinn, M. T. & Huang, P. L., 8 Apr 2016, In : Neuroscience Letters. 618, p. 45-49 5 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Endothelial fcg receptor IIB activation blunts insulin delivery to skeletal muscle to cause insulin resistance in mice

Tanigaki, K., Chambliss, K. L., Yuhanna, I. S., Sacharidou, A., Ahmed, M., Atochin, D. N., Huang, P. L., Shaul, P. W. & Mineo, C., 1 Jul 2016, In : Diabetes. 65, 7, p. 1996-2005 10 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Neuroprotective effects of p-tyrosol after the global cerebral ischemia in rats

Atochin, D. N., Chernysheva, G. A., Smolyakova, V. I., Osipenko, A. N., Logvinov, S. V., Zhdankina, A. A., Sysolyatin, S. V., Kryukov, Y. A., Anfinogenova, Y., Plotnikova, T. M. & Plotnikov, M. B., 15 Jun 2016, In : Phytomedicine. 23, 7, p. 784-792 9 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)
2015

Nitric oxide and mitochondria in metabolic syndrome

Litvinova, L., Atochin, D. N., Fattakhov, N., Vasilenko, M., Zatolokin, P. & Kirienkova, E., 2015, In : Frontiers in Physiology. 6, FEB, 20.

Research output: Contribution to journalReview article

46 Citations (Scopus)
2014

Endothelial dysfunction abrogates the efficacy of normobaric hyperoxia in stroke

Shin, H. K., Oka, F., Kim, J. H., Atochin, D., Huang, P. L. & Ayata, C., 12 Nov 2014, In : Journal of Neuroscience. 34, 46, p. 15200-15207 8 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Phosphomimetic modulation of eNOS improves myocardial reperfusion and mimics cardiac postconditioning in mice

Pong, T., Scherrer-Crosbie, M., Atochin, D. N., Bloch, K. D. & Huang, P. L., 21 Jan 2014, In : PLoS One. 9, 1, e85946.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Role of adiponectin and proinflammatory gene expression in adipose tissue chronic inflammation in women with metabolic syndrome

Litvinova, L., Atochin, D., Vasilenko, M., Fattakhov, N., Zatolokin, P., Vaysbeyn, I. & Kirienkova, E., 2014, In : Diabetology and Metabolic Syndrome. 6, 1, 137.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Through-skull fluorescence imaging of the brain in a new near-infrared window

Hong, G., Diao, S., Chang, J., Antaris, A. L., Chen, C., Zhang, B., Zhao, S., Atochin, D. N., Huang, P. L., Andreasson, K. I., Kuo, C. J. & Dai, H., 2014, In : Nature Photonics. 8, 9, p. 723-730 8 p.

Research output: Contribution to journalArticle

397 Citations (Scopus)
2013

Anti-Inflammatory Effect of Targeted Delivery of SOD to Endothelium: Mechanism, Synergism with NO Donors and Protective Effects In Vitro and In Vivo

Shuvaev, V. V., Han, J., Tliba, S., Arguiri, E., Christofidou-Solomidou, M., Ramirez, S. H., Dykstra, H., Persidsky, Y., Atochin, D. N., Huang, P. L. & Muzykantov, V. R., 11 Oct 2013, In : PLoS One. 8, 10, e77002.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Cerebral blood volume affects blood-brain barrier integrity in an acute transient stroke model

Huang, S., Kim, J. K., Atochin, D. N., Farrar, C. T., Huang, P. L., Suh, J. Y., Kwon, S. J., Shim, W. H., Cho, H., Cho, G. & Kim, Y. R., Jun 2013, In : Journal of Cerebral Blood Flow and Metabolism. 33, 6, p. 898-905 8 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

C-reactive protein causes insulin resistance in mice through fcg receptor IIB-mediated inhibition of skeletal muscle glucose delivery

Tanigaki, K., Vongpatanasin, W., Barrera, J. A., Atochin, D. N., Huang, P. L., Bonvini, E., Shaul, P. W. & Mineo, C., Mar 2013, In : Diabetes. 62, 3, p. 721-731 11 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Deficient eNOS Phosphorylation is a mechanism for diabetic vascular dysfunction contributing to increased stroke size

Li, Q., Atochin, D., Kashiwagi, S., Earle, J., Wang, A., Mandeville, E., Hayakawa, K., D'Uscio, L. V., Lo, E. H., Katusic, Z., Sessa, W. & Huang, P. L., Nov 2013, In : Stroke. 44, 11, p. 3183-3188 6 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

ENOS phosphorylation on serine 1176 affects insulin sensitivity and adiposity

Kashiwagi, S., Atochin, D. N., Li, Q., Schleicher, M., Pong, T., Sessa, W. C. & Huang, P. L., 8 Feb 2013, In : Biochemical and Biophysical Research Communications. 431, 2, p. 284-290 7 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)

Hyperlipidemia disrupts cerebrovascular reflexes and worsens ischemic perfusion defect

Ayata, C., Shin, H. K., Dileköz, E., Atochin, D. N., Kashiwagi, S., Eikermann-Haerter, K. & Huang, P. L., Jun 2013, In : Journal of Cerebral Blood Flow and Metabolism. 33, 6, p. 954-962 9 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)
2012

A novel hydrogen sulfide-releasing N-methyl-D-aspartate receptor antagonist prevents ischemic neuronal death

Marutani, E., Kosugi, S., Tokuda, K., Khatri, A., Nguyen, R., Atochin, D. N., Kida, K., Van Leyen, K., Arai, K. & Ichinose, F., 14 Sep 2012, In : Journal of Biological Chemistry. 287, 38, p. 32124-32135 12 p.

Research output: Contribution to journalArticle

50 Citations (Scopus)
2011

[Interaction of neuronal NOS and catecholamines in regulation of expression of proteins of apoptosis by vasopressinergic hypothalamic neurons].

Chernigovskaia, E. V., Iamova, L. A., Atochin, D., Huang, P. & Glazova, M. V., May 2011, In : Zhurnal Evolyutsionnoi Biokhimii i Fiziologii. 47, 3, p. 232-238 7 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Delayed paraplegia after spinal cord ischemic injury requires caspase-3 activation in mice

Kakinohana, M., Kida, K., Minamishima, S., Atochin, D. N., Huang, P. L., Kaneki, M. & Ichinose, F., Aug 2011, In : Stroke. 42, 8, p. 2302-2307 6 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Immunohistochemical expression of Bcl-2, p53 and caspase-9 in hypothalamus magnocellular centers of nNOS knockout mice following water deprivation

Chernigovskaya, E., Atochin, D., Yamova, L., Huang, P. & Glazova, M., Oct 2011, In : Biotechnic and Histochemistry. 86, 5, p. 333-339 7 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Nitric oxide synthase 3 deficiency limits adverse ventricular remodeling after pressure overload in insulin resistance

Kurtz, B., Thibault, H. B., Raher, M. J., Popovich, J. R., Cawley, S., Atochin, D. N., Hayton, S., Shakartzi, H. R., Huang, P. L., Bloch, K. D., Buys, E. & Scherrer-Crosbie, M., Nov 2011, In : American Journal of Physiology - Heart and Circulatory Physiology. 301, 5

Research output: Contribution to journalArticle

7 Citations (Scopus)

Optical coherence tomography for the quantitative study of cerebrovascular physiology

Srinivasan, V. J., Atochin, D. N., Radhakrishnan, H., Jiang, J. Y., Ruvinskaya, S., Wu, W., Barry, S., Cable, A. E., Ayata, C., Huang, P. L. & Boas, D. A., Jun 2011, In : Journal of Cerebral Blood Flow and Metabolism. 31, 6, p. 1339-1345 7 p.

Research output: Contribution to journalArticle

54 Citations (Scopus)

Role of endothelial nitric oxide in cerebrovascular regulation

Atochin, D. N. & Huang, P. L., Sep 2011, In : Current Pharmaceutical Biotechnology. 12, 9, p. 1334-1342 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)
2010

Endothelial nitric oxide synthase transgenic models of endothelial dysfunction

Atochin, D. N. & Huang, P. L., Nov 2010, In : Pflugers Archiv European Journal of Physiology. 460, 6, p. 965-974 10 p.

Research output: Contribution to journalReview article

77 Citations (Scopus)

Soluble guanylate cyclase α1β1 limits stroke size and attenuates neurological injury

Atochin, D. N., Yuzawa, I., Li, Q., Rauwerdink, K. M., Malhotra, R., Chang, J., Brouckaert, P., Ayata, C., Moskowitz, M. A., Bloch, K. D., Huang, P. L. & Buys, E. S., Aug 2010, In : Stroke. 41, 8, p. 1815-1819 5 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)
2008

Cerebrovascular thromboprophylaxis in mice by erythrocyte-coupled tissue-type plasminogen activator

Danielyan, K., Ganguly, K., Ding, B. S., Atochin, D., Zaitsev, S., Murciano, J. C., Huang, P. L., Kasner, S. E., Cines, D. B. & Muzykantov, V. R., 30 Sep 2008, In : Circulation. 118, 14, p. 1442-1449 8 p.

Research output: Contribution to journalArticle

59 Citations (Scopus)

Contributions of nitric oxide synthase isoforms to pulmonary oxygen toxicity, local vs. mediated effects

Demchenko, I. T., Atochin, D. N., Gutsaeva, D. R., Godfrey, R. R., Huang, P. L., Piantadosi, C. A. & Allen, B. W., May 2008, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 294, 5

Research output: Contribution to journalArticle

26 Citations (Scopus)

Effects of neuroglobin overexpression on acute brain injury and long-term outcomes after focal cerebral ischemia

Wang, X., Liu, J., Zhu, H., Tejima, E., Tsuji, K., Murata, Y., Atochin, D. N., Huang, P. L., Zhang, C. & Lo, E. H., 1 Jun 2008, In : Stroke. 39, 6, p. 1869-1874 6 p.

Research output: Contribution to journalArticle

123 Citations (Scopus)

In vivo quantification of transvascular water exchange during the acute phase of permanent stroke

Kim, Y. R., Tejima, E., Huang, S., Atochin, D. N., Dai, G., Lo, E. H., Huang, P. L., Bogdanov, A. & Rosen, B. R., Oct 2008, In : Magnetic Resonance in Medicine. 60, 4, p. 813-821 9 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)
2007

Endothelial nitric oxide synthase S1179 phosphorylation improves cerebral blood flow and reduces infarct size in focal cerebral ischemia

Hwa, K. S., Atochin, D. N., Lee, S. W., Huang, P. L., Moskowitz, M. A. & Ayata, C., 13 Nov 2007, In : Journal of Cerebral Blood Flow and Metabolism. 27, SUPPL. 1

Research output: Contribution to journalArticle

Hypercholesterolemia worsens the blood flow deficit in focal cerebral ischemia in the absence of atherosclerosis

Hwa, K. S., Li, J. A. L., Atochin, D. N., Moskowitz, M. A., Huang, P. L. & Ayata, C., 13 Nov 2007, In : Journal of Cerebral Blood Flow and Metabolism. 27, SUPPL. 1

Research output: Contribution to journalArticle

Reduction of hippocampal cell death and proteolytic responses in tissue plasminogen activator knockout mice after transient global cerebral ischemia

Lee, S. R., Lok, J., Rosell, A., Kim, H. Y., Murata, Y., Atochin, D., Huang, P. L., Wang, X., Ayata, C., Moskowitz, M. A. & Lo, E. H., 30 Nov 2007, In : Neuroscience. 150, 1, p. 50-57 8 p.

Research output: Contribution to journalArticle

25 Citations (Scopus)

The phosphorylation state of eNOS modulates vascular reactivity and outcome of cerebral ischemia in vivo

Atochin, D. N., Wang, A., Liu, V. W. T., Critchlow, J. D., Dantas, A. P. V., Looft-Wilson, R., Murata, T., Salomone, S., Hwa, K. S., Ayata, C., Moskowitz, M. A., Michel, T., Sessa, W. C. & Huang, P. L., 2 Jul 2007, In : Journal of Clinical Investigation. 117, 7, p. 1961-1967 7 p.

Research output: Contribution to journalArticle

124 Citations (Scopus)
2005

Tissue plasminogen activator promotes matrix metalloproteinase-9 upregulation after focal cerebral ischemia

Tsuji, K., Aoki, T., Tejima, E., Arai, K., Lee, S. R., Atochin, D. N., Huang, P. L., Wang, X., Montaner, J. & Lo, E. H., Sep 2005, In : Stroke. 36, 9, p. 1954-1959 6 p.

Research output: Contribution to journalArticle

184 Citations (Scopus)
2004

Mouse model of microembolic stroke and reperfusion

Atochin, D. N., Murciano, J. C., Gürsoy-Özdemir, Y., Krasik, T., Noda, F., Ayata, C., Dunn, A. K., Moskowitz, M. A., Huang, P. L. & Muzykantov, V. R., Sep 2004, In : Stroke. 35, 9, p. 2177-2182 6 p.

Research output: Contribution to journalArticle

45 Citations (Scopus)
2003

Contributions of endothelial and neuronal nitric oxide synthases to cerebrovascular responses to hyperoxia

Atochin, D. N., Demchenko, I. T., Astern, J., Boso, A. E., Piantadosi, C. A. & Huang, P. L., 1 Oct 2003, In : Journal of Cerebral Blood Flow and Metabolism. 23, 10, p. 1219-1226 8 p.

Research output: Contribution to journalArticle

75 Citations (Scopus)
9 Citations (Scopus)

Oxygen seizure latency and peroxynitrite formation in mice lacking neuronal or endothelial nitric oxide synthases

Demchenko, I. T., Atochin, D. N., Boso, A. E., Astern, J., Huang, P. L. & Piantadosi, C. A., 19 Jun 2003, In : Neuroscience Letters. 344, 1, p. 53-56 4 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

Rapid cerebral ischemic preconditioning in mice deficient in endothelial and neuronal nitric oxide synthases

Atochin, D. N., Clark, J., Demchenko, I. T., Moskowitz, M. A. & Huang, P. L., 1 May 2003, In : Stroke. 34, 5, p. 1299-1303 5 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)